Effect Sizes of Deletions and Duplications on Autism Risk Across the Genome

Deleterious copy number variants (CNVs) are identified in up to 20% of individuals with autism. However, levels of autism risk conferred by most rare CNVs remain unknown. The authors recently developed statistical models to estimate the effect size on IQ of all CNVs, including undocumented ones. In...

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Vydáno v:	The American journal of psychiatry Ročník 178; číslo 1; s. 87
Hlavní autoři:	Douard, Elise, Zeribi, Abderrahim, Schramm, Catherine, Tamer, Petra, Loum, Mor Absa, Nowak, Sabrina, Saci, Zohra, Lord, Marie-Pier, Rodríguez-Herreros, Borja, Jean-Louis, Martineau, Moreau, Clara, Loth, Eva, Schumann, Gunter, Pausova, Zdenka, Elsabbagh, Mayada, Almasy, Laura, Glahn, David C, Bourgeron, Thomas, Labbe, Aurélie, Paus, Tomas, Mottron, Laurent, Greenwood, Celia M T, Huguet, Guillaume, Jacquemont, Sébastien
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.01.2021
Témata:	Adolescent Adult Autistic Disorder - genetics Case-Control Studies Child DNA Copy Number Variations - genetics Female Gene Deletion Gene Duplication - genetics Genetic Predisposition to Disease - genetics Genome - genetics Humans Intelligence - genetics Male Risk Factors Copy Number Variants IQ Autism Spectrum Disorder
ISSN:	1535-7228, 1535-7228
On-line přístup:	Zjistit podrobnosti o přístupu
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