d-Glucuronate and d-Glucuronate Glycal Acceptors for the Scalable Synthesis of d-GlcN-α-1,4-d-GlcA Disaccharides and Modular Assembly of Heparan Sulfate

Reported herein is a scalable chemical synthesis of disaccharidebuilding blocks for heparan sulfate (HS) oligosaccharide assembly.The use of d-glucuronate-based acceptors for dehydrativeglycosylation with d-glucosamine partners is explored, enablingdiastereoselective synthesis of appropriately prote...

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Vydané v:	Journal of organic chemistry Ročník 88; číslo 15; s. 11130 - 11139
Hlavní autori:	Pongener, Imlirenla, Miller, Gavin J. J.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	WASHINGTON Amer Chemical Soc 04.08.2023
Predmet:	Chemistry Chemistry, Organic Physical Sciences Science & Technology HERPES-SIMPLEX-VIRUS ACTIVATION ACID OLIGOSACCHARIDES MOIETY STRATEGY DODECASACCHARIDES GLYCOSYL PHOSPHATES CHEMICAL-SYNTHESIS BINDING
ISSN:	0022-3263, 1520-6904, 1520-6904
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