A human milk oligosaccharide prevents intestinal inflammation in adulthood via modulating gut microbial metabolism

At present, neither basic research nor clinical studies have revealed the exact biological functions or mechanisms of action of individual oligosaccharides during development or in adulthood. Thus, it remains largely unknown whether human milk oligosaccharides could serve as effective therapeutics f...

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Vydáno v:	mBio Ročník 15; číslo 4; s. e0029824
Hlavní autoři:	Schalich, Kasey M., Buendia, Matthew A., Kaur, Harpreet, Choksi, Yash A., Washington, M. Kay, Codreanu, Gabriela S., Sherrod, Stacy D., McLean, John A., Peek, Jr, Richard M., Acra, Sari A., Townsend, Steven D., Yan, Fang
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States American Society for Microbiology 10.04.2024
Témata:	2′-fucosyllactose Adult Animals Antibiotics Bacteria Bifidobacterium infantis Bifidobacterium longum subsp. infantis Breast milk Colitis - prevention & control Colitis, Ulcerative - metabolism Colon Digestive system Drinking water Fecal microflora Feces Gastrointestinal Microbiome Gastrointestinal tract Gut microbiota Health care Homeostasis Host-Microbial Interactions human milk oligosaccharide Humans Immune system Inflammation Inflammatory bowel disease inflammatory bowel diseases intestinal barrier Intestinal microflora Intestine Metabolic pathways Metabolism Metabolites Metabolomics Mice Microbiomes Microbiota Milk, Human Oligosaccharides Oligosaccharides - metabolism Oxidative stress pantothenate Pantothenic Acid - analogs & derivatives Patients Research Article Tumor necrosis factor-TNF Ulcerative colitis the gut microbiota inflammatory bowel diseases intestinal barrier 2′-fucosyllactose human milk oligosaccharide pantothenate Bifidobacterium longum subsp. infantis
ISSN:	2150-7511, 2161-2129, 2150-7511
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