Emergence of glass-like behavior in Markov state models of protein folding dynamics

The extent to which glass-like kinetics govern dynamics in protein folding has been heavily debated. Here, we address the subject with an application of space-time perturbation theory to the dynamics of protein folding Markov state models. Borrowing techniques from the s-ensemble method, we argue th...

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Bibliographic Details

Published in:	Journal of the American Chemical Society Vol. 135; no. 15; p. 5501
Main Authors:	Weber, Jeffrey K, Jack, Robert L, Pande, Vijay S
Format:	Journal Article
Language:	English
Published:	United States 17.04.2013
Subjects:	Glass - chemistry Markov Chains Models, Molecular Protein Folding Protein Structure, Tertiary Proteins - chemistry
ISSN:	1520-5126, 1520-5126
Online Access:	Get more information
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