Sporadic Creutzfeldt-Jakob disease mimicking variant Creutzfeldt-Jakob disease

The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging f...

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Bibliographic Details
Published in:Archives of neurology (Chicago) Vol. 60; no. 5; p. 767
Main Authors: Martindale, Jennifer, Geschwind, Michael D, De Armond, Stephen, Young, Geoffrey, Dillon, W P, Henry, Roland, Uyehara-Lock, Jane H, Gaskin, David A, Miller, Bruce L
Format: Journal Article
Language:English
Published: United States 01.05.2003
Subjects:
Adult
Biopsy
Brain - pathology
Creutzfeldt-Jakob Syndrome - classification
Creutzfeldt-Jakob Syndrome - pathology
Diagnosis, Differential
Electroencephalography
Female
Humans
Magnetic Resonance Imaging
Pulvinar - pathology
ISSN:0003-9942
Online Access:Get more information
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Summary:The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). Results of a repeated electroencephalogram were suggestive of sCJD, and a subsequent brain biopsy confirmed this diagnosis. This case cautions against relying solely on T2- and diffusion-weighted pulvinar hyperintensity and clinical features to differentiate between vCJD and sCJD, and further supports established diagnostic criteria for vCJD.
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ISSN:0003-9942
DOI:10.1001/archneur.60.5.767