Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure

This study characterized the pharmacokinetics of novel 100-mg levofloxacin dispersible tablets in 24 children aged <5 years who had household multidrug-resistant tuberculosus (MDR-TB) exposure. The current data were pooled with previously published data from children ( = 109) with MDR-TB receivi...

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Vydáno v:	Antimicrobial agents and chemotherapy Ročník 63; číslo 4
Hlavní autoři:	Garcia-Prats, Anthony J, Purchase, Susan E, Osman, Muhammad, Draper, Heather R, Schaaf, H Simon, Wiesner, Lubbe, Denti, Paolo, Hesseling, Anneke C
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.04.2019
Témata:	Antitubercular Agents - administration & dosage Antitubercular Agents - adverse effects Antitubercular Agents - pharmacokinetics Biological Availability Child, Preschool Female Humans Infant Levofloxacin - administration & dosage Levofloxacin - adverse effects Levofloxacin - pharmacokinetics Male Placebos Tablets Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - prevention & control bioavailability children levofloxacin formulation pharmacokinetics multidrug-resistant tuberculosis dispersible tablets
ISSN:	1098-6596, 1098-6596
On-line přístup:	Zjistit podrobnosti o přístupu
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