A method for selective enrichment and analysis of nitrotyrosine-containing peptides in complex proteome samples

Elevated levels of protein tyrosine nitration have been found in various neurodegenerative diseases and age-related pathologies. Until recently, however, the lack of an efficient enrichment method has prevented the analysis of this important low-level protein modification. We have developed a method...

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Veröffentlicht in:	Journal of proteome research Jg. 6; H. 6; S. 2257
Hauptverfasser:	Zhang, Qibin, Qian, Wei-Jun, Knyushko, Tatyana V, Clauss, Therese R W, Purvine, Samuel O, Moore, Ronald J, Sacksteder, Colette A, Chin, Mark H, Smith, Desmond J, Camp, 2nd, David G, Bigelow, Diana J, Smith, Richard D
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.06.2007
Schlagworte:	Amino Acid Sequence Animals Brain Chemistry Cattle Chromatography, Liquid Humans Mass Spectrometry Mice Molecular Sequence Data Peptides - chemistry Proteins - chemistry Proteome - chemistry Proteomics - methods Tyrosine - analogs & derivatives Tyrosine - analysis
ISSN:	1535-3893
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