Combined Catalysis for Engineering Bioinspired, Lignin-Based, Long-Lasting, Adhesive, Self-Mending, Antimicrobial Hydrogels

The engineering of multifunctional biomaterials using a facile sustainable methodology that follows the principles of green chemistry is still largely unexplored but would be very beneficial to the world. Here, the employment of catalytic reactions in combination with biomass-derived starting materi...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS nano Ročník 14; číslo 12; s. 17004 - 17017
Hlavní autoři: Afewerki, Samson, Wang, Xichi, Ruiz-Esparza, Guillermo U, Tai, Cheuk-Wai, Kong, Xueying, Zhou, Shengyang, Welch, Ken, Huang, Ping, Bengtsson, Rhodel, Xu, Chao, Strømme, Maria
Médium: Journal Article
Jazyk:angličtina
Vydáno: American Chemical Society 22.12.2020
Témata:
adhesive
antimicrobial
bioinspired
combined catalysis
Engineering Science with specialization in Nanotechnology and Functional Materials
hydrogel
lignin
self-healing
Teknisk fysik med inriktning mot nanoteknologi och funktionella material
antimicrobial
hydrogel
lignin
bioinspired
adhesive
combined catalysis
self-healing
ISSN:1936-0851, 1936-086X, 1936-086X
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:The engineering of multifunctional biomaterials using a facile sustainable methodology that follows the principles of green chemistry is still largely unexplored but would be very beneficial to the world. Here, the employment of catalytic reactions in combination with biomass-derived starting materials in the design of biomaterials would promote the development of eco-friendly technologies and sustainable materials. Herein, we disclose the combination of two catalytic cycles (combined catalysis) comprising oxidative decarboxylation and quinone-catechol redox catalysis for engineering lignin-based multifunctional antimicrobial hydrogels. The bioinspired design mimics the catechol chemistry employed by marine mussels in nature. The resultant multifunctional sustainable hydrogels (1) are robust and elastic, (2) have strong antimicrobial activity, (3) are adhesive to skin tissue and various other surfaces, and (4) are able to self-mend. A systematic characterization was carried out to fully elucidate and understand the facile and efficient catalytic strategy and the subsequent multifunctional materials. Electron paramagnetic resonance analysis confirmed the long-lasting quinone-catechol redox environment within the hydrogel system. Initial in vitro biocompatibility studies demonstrated the low toxicity of the hydrogels. This proof-of-concept strategy could be developed into an important technological platform for the eco-friendly, bioinspired design of other multifunctional hydrogels and their use in various biomedical and flexible electronic applications.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1936-0851
1936-086X
1936-086X
DOI:10.1021/acsnano.0c06346