Synthesis and Bioactivity of Reduced Chalcones Containing Sulfonamide Side Chains

The effect on the bioactivity of antibacterial sulfonamide drugs against malaria and tuberculosis via an increase of the lipid solubility groups by condensation with a reduced chalcone was investigated. Sulfonamide derivatives (8a-8d) were obtained via a 1,3-diarylpropane scaffold, prepared by reduc...

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Vydané v:	Journal of natural products (Washington, D.C.) Ročník 81; číslo 1; s. 41 - 48
Hlavní autori:	Noreljaleel, Anwar E. M., Wilhelm, A., Bonnet, S. L., van der Westhuizen, J. H.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	WASHINGTON Amer Chemical Soc 26.01.2018
Predmet:	Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Plant Sciences Science & Technology MALARIA INHIBITION ANTIBACTERIAL ACTIVITY DERIVATIVES TUBERCULOSIS
ISSN:	0163-3864, 1520-6025, 1520-6025
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