Synthesis and Bioactivity of Reduced Chalcones Containing Sulfonamide Side Chains

The effect on the bioactivity of antibacterial sulfonamide drugs against malaria and tuberculosis via an increase of the lipid solubility groups by condensation with a reduced chalcone was investigated. Sulfonamide derivatives (8a-8d) were obtained via a 1,3-diarylpropane scaffold, prepared by reduc...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) Jg. 81; H. 1; S. 41 - 48
Hauptverfasser:	Noreljaleel, Anwar E. M., Wilhelm, A., Bonnet, S. L., van der Westhuizen, J. H.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	WASHINGTON Amer Chemical Soc 26.01.2018
Schlagworte:	Chemistry, Medicinal Life Sciences & Biomedicine Pharmacology & Pharmacy Plant Sciences Science & Technology MALARIA INHIBITION ANTIBACTERIAL ACTIVITY DERIVATIVES TUBERCULOSIS
ISSN:	0163-3864, 1520-6025, 1520-6025
Online-Zugang:	Weitere Angaben
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