Efficient one-pot synthesis of highly substituted pyridin-2(1H)-ones via the Vilsmeier-Haack reaction of 1-acetyl,1-carbamoyl cyclopropanes

A facile and efficient one-pot synthesis of highly substituted pyridin-2(1H)-ones is developed via the Vilsmeier-Haack reaction of readily available 1-acetyl,1-carbamoyl cyclopropanes, and a mechanism involving sequential ring-opening, haloformylation, and intramolecular nucleophilic cyclization rea...

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Vydané v:	Organic letters Ročník 9; číslo 12; s. 2421 - 2423
Hlavní autori:	Pan, Wei, Dong, Dewen, Wang, Kewei, Zhang, Jie, Wu, Rigenhada, Xiang, Dexuan, Liu, Qun
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	WASHINGTON Amer Chemical Soc 07.06.2007
Predmet:	Chemistry Chemistry, Organic Crystallography, X-Ray Cyclopropanes - chemistry Models, Molecular Molecular Structure Physical Sciences Pyridones - chemical synthesis Pyridones - chemistry Science & Technology Stereoisomerism CYCLOADDITION PYRIDINE RINGS STRATEGY 2-PYRIDONE INHIBITORS DERIVATIVES PYRIDONES
ISSN:	1523-7060
On-line prístup:	Zistit podrobnosti o prístupe
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