Efficient one-pot synthesis of highly substituted pyridin-2(1H)-ones via the Vilsmeier-Haack reaction of 1-acetyl,1-carbamoyl cyclopropanes

A facile and efficient one-pot synthesis of highly substituted pyridin-2(1H)-ones is developed via the Vilsmeier-Haack reaction of readily available 1-acetyl,1-carbamoyl cyclopropanes, and a mechanism involving sequential ring-opening, haloformylation, and intramolecular nucleophilic cyclization rea...

Full description

Saved in:

Bibliographic Details
Published in:	Organic letters Vol. 9; no. 12; pp. 2421 - 2423
Main Authors:	Pan, Wei, Dong, Dewen, Wang, Kewei, Zhang, Jie, Wu, Rigenhada, Xiang, Dexuan, Liu, Qun
Format:	Journal Article
Language:	English
Published:	WASHINGTON Amer Chemical Soc 07.06.2007
Subjects:	Chemistry Chemistry, Organic Crystallography, X-Ray Cyclopropanes - chemistry Models, Molecular Molecular Structure Physical Sciences Pyridones - chemical synthesis Pyridones - chemistry Science & Technology Stereoisomerism CYCLOADDITION PYRIDINE RINGS STRATEGY 2-PYRIDONE INHIBITORS DERIVATIVES PYRIDONES
ISSN:	1523-7060
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!