Effect of Pembrolizumab After Stereotactic Body Radiotherapy vs Pembrolizumab Alone on Tumor Response in Patients With Advanced Non-Small Cell Lung Cancer: Results of the PEMBRO-RT Phase 2 Randomized Clinical Trial

Many patients with advanced non-small cell lung cancer (NSCLC) receiving immunotherapy show primary resistance. High-dose radiotherapy can lead to increased tumor antigen release, improved antigen presentation, and T-cell infiltration. This radiotherapy may enhance the effects of checkpoint inhibiti...

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Bibliographic Details
Published in:JAMA oncology Vol. 5; no. 9; p. 1276
Main Authors: Theelen, Willemijn S M E, Peulen, Heike M U, Lalezari, Ferry, van der Noort, Vincent, de Vries, Jeltje F, Aerts, Joachim G J V, Dumoulin, Daphne W, Bahce, Idris, Niemeijer, Anna-Larissa N, de Langen, Adrianus J, Monkhorst, Kim, Baas, Paul
Format: Journal Article
Language:English
Published: United States 01.09.2019
ISSN:2374-2445, 2374-2445
Online Access:Get more information
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