Direct Reprogramming of Mouse Fibroblasts to Osteoblast-like Cells Using Runx2/Dlx5 Factors on Engineered Stiff Hydrogels

Direct reprogramming of somatic cells into functional cells still faces major limitations in terms of efficiency and achieving functional maturity of the reprogramed cells. While different approaches have been developed commonly based on exploiting biochemical signals, introducing appropriate mechan...

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Vydané v:	ACS applied materials & interfaces Ročník 15; číslo 51; s. 59209
Hlavní autori:	Zhang, Junwei, Wang, Yao, Guo, Jing, Zhang, Nihui, He, Jing, Zhou, Zongke, Wu, Fang
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 27.12.2023
Predmet:	mechanical microenvironment transcriptional factors reprogramming efficiency cell therapy direct reprogramming
ISSN:	1944-8252, 1944-8252
On-line prístup:	Zistit podrobnosti o prístupe
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