Side Reactions with an Equilibrium Constraint: Detailed Mechanism of the Substitution Reaction of Tetraplatin with dGMP as a Starting Step of the Platinum(IV) Reduction Process

Two possible pathways of the substitution reaction within the reduction process of the Pt (DACH)Cl by dGMP are compared: associative reaction course and autocatalytic Basolo-Pearson mechanisms. Since two forms: single-protonated and fully deprotonated phosphate group of dGMP are present in equilibri...

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Bibliographic Details

Published in:	The journal of physical chemistry. B Vol. 121; no. 17; p. 4400
Main Authors:	Šebesta, Filip, Burda, Jaroslav V
Format:	Journal Article
Language:	English
Published:	United States 04.05.2017
Subjects:	Deoxyguanine Nucleotides - chemistry Organoplatinum Compounds - chemistry Platinum Compounds - chemistry Quantum Theory
ISSN:	1520-5207, 1520-5207
Online Access:	Get more information
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