High-Dimensional Operator Learning for Molecular Density Functional Theory

Classical density functional theory (cDFT) provides a systematic framework to predict the structure and thermodynamic properties of chemical systems through molecular density profiles. Whereas the statistical-mechanical framework is theoretically rigorous, its applications are often constrained by c...

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Vydané v:Journal of chemical theory and computation Ročník 21; číslo 12; s. 5905
Hlavní autori: Yang, Jinni, Pan, Runtong, Sun, Jikai, Wu, Jianzhong
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: United States 24.06.2025
ISSN:1549-9626, 1549-9626
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Shrnutí:Classical density functional theory (cDFT) provides a systematic framework to predict the structure and thermodynamic properties of chemical systems through molecular density profiles. Whereas the statistical-mechanical framework is theoretically rigorous, its applications are often constrained by challenges in formulating a reliable free-energy functional and the complexity of solving multidimensional integro-differential equations. In this work, we established a convolutional operator learning method that effectively separates the high-dimensional molecular density profile into lower-dimensional components, thereby exponentially reducing the vast input space. The operator learning network demonstrates exceptional learning capabilities, accurately mapping the relationship between the molecular density profile and its one-body direct correlation function for an atomistic polarizable model of carbon dioxide. The machine-learning procedure can be generalized to more complex molecular systems, offering high-precision operator-cDFT calculations at a low computational cost.
Bibliografia:ObjectType-Article-1
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ISSN:1549-9626
1549-9626
DOI:10.1021/acs.jctc.5c00484