Use of Peptide Microarrays for Fast and Informative Profiling of Therapeutic Antibody Formulation Conditions

Methods to optimize the solution behavior of therapeutic proteins are frequently time-consuming, provide limited information, and often use milligram quantities of material. Here, we present a simple, versatile method that provides valuable information to guide the identification and comparison of f...

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Vydané v:	Molecular pharmaceutics Ročník 18; číslo 11; s. 4131
Hlavní autori:	Austerberry, James, Edwards, John, Eyes, Tim, Derrick, Jeremy P
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.11.2021
Predmet:	Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - therapeutic use Biological Products - chemistry Biological Products - therapeutic use Chemistry, Pharmaceutical - methods Humans Machine Learning Peptides - chemistry Protein Array Analysis - methods Protein Stability Single-Chain Antibodies - chemistry Single-Chain Antibodies - therapeutic use formulation microarray peptide biopharmaceutical monoclonal antibody
ISSN:	1543-8392, 1543-8392
On-line prístup:	Zistit podrobnosti o prístupe
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