BoostDILI: Extreme Gradient Boost-Powered Drug-Induced Liver Injury Prediction and Structural Alerts Generation

Over the past 60 years, drug-induced liver injury (DILI) has played a key role in the withdrawal of marketed drugs due to safety concerns. Early prediction of DILI is crucial for developing safer pharmaceuticals, yet current and testing methods are complex and cumbersome. In this study, we developed...

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Veröffentlicht in:	Chemical research in toxicology Jg. 38; H. 5; S. 865
Hauptverfasser:	Chutia, Hillul, Borah, Gori Sankar, Mahanta, Hridoy Jyoti, Nagamani, Selvaraman
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 19.05.2025
Schlagworte:	Boosting Machine Learning Algorithms Chemical and Drug Induced Liver Injury Humans Machine Learning Pharmaceutical Preparations - chemistry United States Food and Drug Administration
ISSN:	1520-5010, 1520-5010
Online-Zugang:	Weitere Angaben
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