Bovine coccidiosis and molecular characterization of pathogenic Eimeria species in dairy cattle on Grati--Pasuruan, East Java, Indonesia.

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Titel: Bovine coccidiosis and molecular characterization of pathogenic Eimeria species in dairy cattle on Grati--Pasuruan, East Java, Indonesia.
Autoren: Poedji Hastutiek1,2 poedji-h@fkh.unair.ac.id, Tri Suwanti, Lucia1,3, Endang Suprihati1, Nunuk Dyah Retno Lastuti1,4, Hari Wardhana, April5, Munawer Pradana6, Kurniawan, Muhammad Ahdi6
Quelle: Open Veterinary Journal. 2025, Vol. 15 Issue 4, p1549-1556. 8p.
Publikationsart: Article
Schlagworte: Dairy cattle, Protozoan diseases, Polymerase chain reaction, Milk yield, Gene amplification
Geografische Kategorien: Papua (Indonesia)
Author-Supplied Keywords: Coccidiosis
East Java
Eimeria species
Grati
Abstract: Background: Coccidiosis, caused by Eimeria spp., is a protozoan infection that rapidly spreads in the gastrointestinal tract of cattle. Coccidiosis requires attention from all parties, including the government, because it remains a neglected disease that impacts milk and meat production, potentially compromising food security and nutrition. The disease is frequently observed on farms with poor management systems, inadequate housing sanitation, and suboptimal environmental conditions. Eimeria spp. primarily cause mortality in calves less than 1 year old. Infection occurs when cattle consume sporulated oocysts that contaminate their water and feed, and this is the primary mode of transmission. Aim: This study aimed to identify various species of Eimeria spp. oocysts, followed by molecular characterization to identify pathogenic Eimeria spp. in dairy cattle. Methods: Fresh fecal samples were collected from 100 dairy cattle. Microscopic examination was performed to detect Eimeria using floatation. Molecular characterization of pathogenic Eimeria spp. by Polymerase Chain Reaction. Polymerase chain reaction (PCR) targeting of the ribosomal RNA gene's Internal Transcribed Spacer 1 (ITS-1) region. Result: The analysis indicated that 47 samples tested positive for the presence of Eimeria spp. oocysts. The analysis revealed five different species of Eimeria. Four samples with oocyst concentrations ranging from 250 to 2,500/ml were selected for DNA extraction and amplification, and using conventional PCR methods, Eimeria bovis (238 bp) was identified. Positive results for the molecular characterization of pathogenic Eimeria spp. were obtained using the ITS-1 gene at 238 bp. Conclusion: This study investigated cases of bovine coccidiosis and the molecular characterization of Eimeria species. The prevalence of coccidiosis in dairy cattle is 47%. E. bovis has been characterized using ITS-1, which measures 238 bp, in dairy cattle located in Grati-Pasuruan, East Java, Indonesia. [ABSTRACT FROM AUTHOR]
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Author Affiliations: 1Department of Veterinary Parasitology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
2Entomology Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia
3Toxoplasma Study Group, Institute of Tropical Disease, Universitas Airlangga, Surabaya, Indonesia
4Postgraduate School, Universitas Airlangga, Surabaya, Indonesia
5The Research Organization for Health, National Research and Innovation Agency, Bogor, Indonesia
6Student Master's Program in Veterinary Medicine Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
ISSN: 2226-4485
DOI: 10.5455/OVJ.2025.v15.i4.5
Dokumentencode: 186437462
Datenbank: Veterinary Source
Beschreibung
Abstract:Background: Coccidiosis, caused by Eimeria spp., is a protozoan infection that rapidly spreads in the gastrointestinal tract of cattle. Coccidiosis requires attention from all parties, including the government, because it remains a neglected disease that impacts milk and meat production, potentially compromising food security and nutrition. The disease is frequently observed on farms with poor management systems, inadequate housing sanitation, and suboptimal environmental conditions. Eimeria spp. primarily cause mortality in calves less than 1 year old. Infection occurs when cattle consume sporulated oocysts that contaminate their water and feed, and this is the primary mode of transmission. Aim: This study aimed to identify various species of Eimeria spp. oocysts, followed by molecular characterization to identify pathogenic Eimeria spp. in dairy cattle. Methods: Fresh fecal samples were collected from 100 dairy cattle. Microscopic examination was performed to detect Eimeria using floatation. Molecular characterization of pathogenic Eimeria spp. by Polymerase Chain Reaction. Polymerase chain reaction (PCR) targeting of the ribosomal RNA gene's Internal Transcribed Spacer 1 (ITS-1) region. Result: The analysis indicated that 47 samples tested positive for the presence of Eimeria spp. oocysts. The analysis revealed five different species of Eimeria. Four samples with oocyst concentrations ranging from 250 to 2,500/ml were selected for DNA extraction and amplification, and using conventional PCR methods, Eimeria bovis (238 bp) was identified. Positive results for the molecular characterization of pathogenic Eimeria spp. were obtained using the ITS-1 gene at 238 bp. Conclusion: This study investigated cases of bovine coccidiosis and the molecular characterization of Eimeria species. The prevalence of coccidiosis in dairy cattle is 47%. E. bovis has been characterized using ITS-1, which measures 238 bp, in dairy cattle located in Grati-Pasuruan, East Java, Indonesia. [ABSTRACT FROM AUTHOR]
ISSN:22264485
DOI:10.5455/OVJ.2025.v15.i4.5