View in EDS

Kinetic aspects of virus targeting by nanoparticles in vivo

Saved in:
Bibliographic Details
Title: Kinetic aspects of virus targeting by nanoparticles in vivo
Authors: Zhdanov, Vladimir, 1952
Source: Journal of Biological Physics. 47(2):95-101
Subject Terms: Kinetic model, Nanoparticles, Inhibition, Viral infection, Association
Description: One of the suggested ways of the use of nanoparticles in virology implies their association with and subsequent deactivation of virions. The conditions determining the efficiency of this approach in vivo are now not clear. Herein, I propose the first kinetic model describing the corresponding processes and clarifying these conditions. My analysis indicates that nanoparticles can decrease concentration of infected cells by a factor of one order of magnitude, but this decrease itself (without feedback of the immune system) is insufficient for full eradication of infection. It can, however, induce delay in the progress of infection, and this delay can help to form sufficient feedback of the immune system.
File Description: electronic
Access URL: https://research.chalmers.se/publication/524400
https://research.chalmers.se/publication/524501
https://research.chalmers.se/publication/524501/file/524501_Fulltext.pdf
Database: SwePub
FullText Text:
  Availability: 0
CustomLinks:
  – Url: https://research.chalmers.se/publication/524400#
    Name: EDS - SwePub (s4221598)
    Category: fullText
    Text: View record in SwePub
  – Url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pmc&term=0092-0606[TA]+AND+95[PG]+AND+2021[PDAT]
    Name: FREE - PubMed Central (ISSN based link)
    Category: fullText
    Text: Full Text
    Icon: https://imageserver.ebscohost.com/NetImages/iconPdf.gif
    MouseOverText: Check this PubMed for the article full text.
  – Url: https://resolver.ebscohost.com/openurl?sid=EBSCO:edsswe&genre=article&issn=00920606&ISBN=&volume=47&issue=2&date=20210101&spage=95&pages=95-101&title=Journal of Biological Physics&atitle=Kinetic%20aspects%20of%20virus%20targeting%20by%20nanoparticles%20in%20vivo&aulast=Zhdanov%2C%20Vladimir&id=DOI:10.1007/s10867-021-09570-z
    Name: Full Text Finder
    Category: fullText
    Text: Full Text Finder
    Icon: https://imageserver.ebscohost.com/branding/images/FTF.gif
    MouseOverText: Full Text Finder
  – Url: https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=EBSCO&SrcAuth=EBSCO&DestApp=WOS&ServiceName=TransferToWoS&DestLinkType=GeneralSearchSummary&Func=Links&author=Zhdanov%20V
    Name: ISI
    Category: fullText
    Text: Nájsť tento článok vo Web of Science
    Icon: https://imagesrvr.epnet.com/ls/20docs.gif
    MouseOverText: Nájsť tento článok vo Web of Science
Header DbId: edsswe
DbLabel: SwePub
An: edsswe.oai.research.chalmers.se.0f0b13b4.05da.4f78.a92c.d54bbabdb32b
RelevancyScore: 1004
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 1004.00384521484
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Kinetic aspects of virus targeting by nanoparticles in vivo
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Zhdanov%2C+Vladimir%22">Zhdanov, Vladimir</searchLink>, 1952
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <i>Journal of Biological Physics</i>. 47(2):95-101
– Name: Subject
  Label: Subject Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Kinetic+model%22">Kinetic model</searchLink><br /><searchLink fieldCode="DE" term="%22Nanoparticles%22">Nanoparticles</searchLink><br /><searchLink fieldCode="DE" term="%22Inhibition%22">Inhibition</searchLink><br /><searchLink fieldCode="DE" term="%22Viral+infection%22">Viral infection</searchLink><br /><searchLink fieldCode="DE" term="%22Association%22">Association</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: One of the suggested ways of the use of nanoparticles in virology implies their association with and subsequent deactivation of virions. The conditions determining the efficiency of this approach in vivo are now not clear. Herein, I propose the first kinetic model describing the corresponding processes and clarifying these conditions. My analysis indicates that nanoparticles can decrease concentration of infected cells by a factor of one order of magnitude, but this decrease itself (without feedback of the immune system) is insufficient for full eradication of infection. It can, however, induce delay in the progress of infection, and this delay can help to form sufficient feedback of the immune system.
– Name: Format
  Label: File Description
  Group: SrcInfo
  Data: electronic
– Name: URL
  Label: Access URL
  Group: URL
  Data: <link linkTarget="URL" linkTerm="https://research.chalmers.se/publication/524400" linkWindow="_blank">https://research.chalmers.se/publication/524400</link><br /><link linkTarget="URL" linkTerm="https://research.chalmers.se/publication/524501" linkWindow="_blank">https://research.chalmers.se/publication/524501</link><br /><link linkTarget="URL" linkTerm="https://research.chalmers.se/publication/524501/file/524501_Fulltext.pdf" linkWindow="_blank">https://research.chalmers.se/publication/524501/file/524501_Fulltext.pdf</link>
PLink https://erproxy.cvtisr.sk/sfx/access?url=https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsswe&AN=edsswe.oai.research.chalmers.se.0f0b13b4.05da.4f78.a92c.d54bbabdb32b
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s10867-021-09570-z
    Languages:
      – Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 95
    Subjects:
      – SubjectFull: Kinetic model
        Type: general
      – SubjectFull: Nanoparticles
        Type: general
      – SubjectFull: Inhibition
        Type: general
      – SubjectFull: Viral infection
        Type: general
      – SubjectFull: Association
        Type: general
    Titles:
      – TitleFull: Kinetic aspects of virus targeting by nanoparticles in vivo
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Zhdanov, Vladimir
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-print
              Value: 00920606
            – Type: issn-print
              Value: 15730689
            – Type: issn-locals
              Value: SWEPUB_FREE
            – Type: issn-locals
              Value: CTH_SWEPUB
          Numbering:
            – Type: volume
              Value: 47
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Journal of Biological Physics
              Type: main
ResultId 1