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Gait Speed Reserve in the general population-based 'Good Aging in Skåne' cohort study-distribution and associated factors

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Titel: Gait Speed Reserve in the general population-based 'Good Aging in Skåne' cohort study-distribution and associated factors
Autoren: Lindholm, Beata, Basna, Rani, Ekström, Henrik, Elmståhl, Sölve, Siennicki-Lantz, Arkadiusz
Weitere Verfasser: Lund University, Faculty of Medicine, Department of Clinical Sciences, Malmö, Cognitive disorders, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Malmö, Kognitiv sjukdomsforskning, Originator, Lund University, Profile areas and other strong research environments, Strategic research areas (SRA), MultiPark: Multidisciplinary research focused on Parkinson's disease, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Strategiska forskningsområden (SFO), MultiPark: Multidisciplinary research focused on Parkinson's disease, Originator, Lund University, Faculty of Medicine, Department of Clinical Sciences, Malmö, Geriatrics, Lunds universitet, Medicinska fakulteten, Institutionen för kliniska vetenskaper, Malmö, Geriatrik, Originator, Lund University, Profile areas and other strong research environments, Strategic research areas (SRA), EpiHealth: Epidemiology for Health, Lunds universitet, Profilområden och andra starka forskningsmiljöer, Strategiska forskningsområden (SFO), EpiHealth: Epidemiology for Health, Originator
Quelle: GeroScience. 47:965-976
Schlagwörter: Medical and Health Sciences, Other Medical and Health Sciences, Gerontology, specialising in Medical and Health Sciences, Medicin och hälsovetenskap, Annan medicin och hälsovetenskap, Gerontologi, medicinsk/hälsovetenskaplig inriktning, Clinical Medicine, Geriatrics, Klinisk medicin, Geriatrik
Beschreibung: Gait Speed Reserve (GSR) expresses a difference between fast and comfortable gait speed and may have an impact on everyday functioning. It was also hypothesized as a useful proxy measure of physiological reserve. However, height-normalizing values of GSR and its associated factors have not been evaluated in a general population of older adults. Therefore, we aimed to investigate the distribution of height-normalized GSR (HN-GSR) in an elderly population-based cohort from urban and rural areas (n = 4342) aged 60-93 years and evaluate associated physiological and lifestyle factors. Using linear mixed models, we identified gender and nine modifiable factors as significantly associated with HN-GSR across four age groups. Better handgrip strength, cognition and standing balance, higher physical activity level, larger calf circumference, and less smoking had positive associations with HN-GSR, while female gender, more leg pain, higher weight and, alcohol consumption had opposite effects. The Marginal R2 imply that this model explained 26% of the variance in HN-GSR. Physical activity and handgrip strength varied across age groups in impact on HN-GSR. The differences were however comparatively minor. In this large cohort study of older adults, we proposed for the first time that factors associated with HN-GSR represented multi-domain features that are in line with previous findings reported for GSR. Measuring HN-GSR/GSR may help clinicians identify early physiological impairments or unhealthy lifestyle habits, especially among older women, and may also have safety implications in daily life. Further work is needed to find out if measuring HN-GSR/GSR may be useful in identifying adverse health outcomes and overall physiological reserve.
Zugangs-URL: https://doi.org/10.1007/s11357-024-01318-6
Datenbank: SwePub
Beschreibung
Abstract:Gait Speed Reserve (GSR) expresses a difference between fast and comfortable gait speed and may have an impact on everyday functioning. It was also hypothesized as a useful proxy measure of physiological reserve. However, height-normalizing values of GSR and its associated factors have not been evaluated in a general population of older adults. Therefore, we aimed to investigate the distribution of height-normalized GSR (HN-GSR) in an elderly population-based cohort from urban and rural areas (n = 4342) aged 60-93 years and evaluate associated physiological and lifestyle factors. Using linear mixed models, we identified gender and nine modifiable factors as significantly associated with HN-GSR across four age groups. Better handgrip strength, cognition and standing balance, higher physical activity level, larger calf circumference, and less smoking had positive associations with HN-GSR, while female gender, more leg pain, higher weight and, alcohol consumption had opposite effects. The Marginal R2 imply that this model explained 26% of the variance in HN-GSR. Physical activity and handgrip strength varied across age groups in impact on HN-GSR. The differences were however comparatively minor. In this large cohort study of older adults, we proposed for the first time that factors associated with HN-GSR represented multi-domain features that are in line with previous findings reported for GSR. Measuring HN-GSR/GSR may help clinicians identify early physiological impairments or unhealthy lifestyle habits, especially among older women, and may also have safety implications in daily life. Further work is needed to find out if measuring HN-GSR/GSR may be useful in identifying adverse health outcomes and overall physiological reserve.
ISSN:25092715
25092723
DOI:10.1007/s11357-024-01318-6