Stereoselective Copper-Catalyzed Cross-Coupling of α-CF3-Allylboronic Acids with Diazoketones
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| Title: | Stereoselective Copper-Catalyzed Cross-Coupling of α-CF3-Allylboronic Acids with Diazoketones |
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| Authors: | Kireilis, Tautvydas, 1994, Szabó, Kálmán J., 1962 |
| Source: | Journal of Organic Chemistry. 90(6):2542-2546 |
| Subject Terms: | Allylboronic acid stereoselective, cross-coupling, copper-catalysis., Organic Chemistry, organisk kemi |
| Description: | We have studied copper-catalyzed cross-coupling of chiral α-CF3-substituted allylboronic acids with α-diazoketones. The reaction proceeds with excellent regioselectivity and stereoselectivity via allylic rearrangement. The method is useful for formation a new allylic C(sp3)–C(sp3) bond with high selectivity. The poor yield is a limitation of this reaction. |
| File Description: | electronic |
| Access URL: | https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-239553 https://doi.org/10.1021/acs.joc.4c02869 |
| Database: | SwePub |
Nájsť tento článok vo Web of Science | Abstract: | We have studied copper-catalyzed cross-coupling of chiral α-CF3-substituted allylboronic acids with α-diazoketones. The reaction proceeds with excellent regioselectivity and stereoselectivity via allylic rearrangement. The method is useful for formation a new allylic C(sp3)–C(sp3) bond with high selectivity. The poor yield is a limitation of this reaction. |
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| DOI: | 10.1021/acs.joc.4c02869 |