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Physical activity and sedentary behaviour thresholds for secondary prevention of coronary heart disease: morbidity survival tree analysis.

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Název: Physical activity and sedentary behaviour thresholds for secondary prevention of coronary heart disease: morbidity survival tree analysis.
Autoři: Lönn, Amanda, 1981, Niyonsenga, Theo, Carroll, Suzanne J, Bauman, Adrian, Davey, Rachel, Gallagher, Robyn, Freene, Nicole
Zdroj: Canadian Journal of Cardiology. 41(3):494-503
Témata: Ischemic heart disease, exercise, guidelines, sedentary time, Medicin/Teknik, Medicine/Technology
Popis: BACKGROUND: There are no diagnosis-specific guidelines for moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) for coronary heart disease (CHD). This study aims identifying thresholds of MVPA and SB associated with cardiovascular events.METHODS: Cohort study including individuals with CHD. MVPA and SB were self-reported, and health registers identified cardiovascular events (2006-2022). Survival tree analyses identified thresholds of time associated with the risk of cardiovascular events. Thresholds were explored in Cox regression models.RESULTS: There were 40,156 Australians, 62% men, mean age 70 years. Over 8.3 median years, 3260 non-fatal cardiac events, 5161 total cardiac events, and 14,383 major adverse cardiovascular events (MACE) occurred. Thresholds for MVPA were 122 minutes/week for non-fatal cardiac events and 94 minutes/week for total cardiac events and MACE. Meeting MVPA thresholds was associated with an 18% lower risk for non-fatal cardiac events, 29% lower risk of total cardiac events, and 23% lower risk of MACE than not reaching the thresholds. Thresholds for SB were 4 and 10 hours/day respectively for risk of total cardiac events and MACE. SB below thresholds was associated with a 14% lower risk of total cardiac events and an 18% lower risk of MACE. There were sex-specific thresholds for MVPA and SB.CONCLUSION: To lower cardiovascular event risk, identified MVPA thresholds were lower (94-122 minutes/week) than the public health guidelines (150 minutes/week) in individuals with CHD. The SB thresholds associated with a lower risk of total cardiac events and MACE varied between 4-10 hours/day.
Popis souboru: electronic
Přístupová URL adresa: https://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-8413
https://doi.org/10.1016/j.cjca.2024.11.025
Databáze: SwePub
Popis
Abstrakt:<strong>BACKGROUND:</strong> There are no diagnosis-specific guidelines for moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) for coronary heart disease (CHD). This study aims identifying thresholds of MVPA and SB associated with cardiovascular events.<strong>METHODS:</strong> Cohort study including individuals with CHD. MVPA and SB were self-reported, and health registers identified cardiovascular events (2006-2022). Survival tree analyses identified thresholds of time associated with the risk of cardiovascular events. Thresholds were explored in Cox regression models.<strong>RESULTS:</strong> There were 40,156 Australians, 62% men, mean age 70 years. Over 8.3 median years, 3260 non-fatal cardiac events, 5161 total cardiac events, and 14,383 major adverse cardiovascular events (MACE) occurred. Thresholds for MVPA were 122 minutes/week for non-fatal cardiac events and 94 minutes/week for total cardiac events and MACE. Meeting MVPA thresholds was associated with an 18% lower risk for non-fatal cardiac events, 29% lower risk of total cardiac events, and 23% lower risk of MACE than not reaching the thresholds. Thresholds for SB were 4 and 10 hours/day respectively for risk of total cardiac events and MACE. SB below thresholds was associated with a 14% lower risk of total cardiac events and an 18% lower risk of MACE. There were sex-specific thresholds for MVPA and SB.<strong>CONCLUSION:</strong> To lower cardiovascular event risk, identified MVPA thresholds were lower (94-122 minutes/week) than the public health guidelines (150 minutes/week) in individuals with CHD. The SB thresholds associated with a lower risk of total cardiac events and MACE varied between 4-10 hours/day.
ISSN:0828282X
19167075
DOI:10.1016/j.cjca.2024.11.025