Podrobná bibliografie
| Název: |
Associations of autozygosity with a broad range of human phenotypes |
| Autoři: |
Clark, D.W., Okada, Y., Moore, K.H.S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C.L.K., Lin, K., Zhao, J.H., Deelan, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T.M., Baumbach, C., Biino, G., Bixley, M.J., Brumat, M., Chai, J.F., Corre, T., Cousminer, D.L., Dekker, A.M., Eccles, D.A., van Eijk, K.R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S.D., de Haan, H.G., Harris, S.E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I.E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M.E., Li, S.A., Li-Gao, R., Mahajan, A.L., Matsuda, K., Meidtner, K., Meng, W., Montasser, M.E., van der Most, P.J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R.B., Priyanka, T.D.S., Rizzi, F., Salvi, E., Sapkota, B.R., Shriner, D., Skotte, L., Smart, M.C., Smith, A.V., van der Spek, A., Spracklen, C.N., Strawbridge, R.J., Tajuddin, S.M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H.R., Wootton, R.E., Yanek, L.R., Yao, J., Yousri, N.A., Zhao, W., Adeyemo, A.A., Albert, M.L., Afaq, S., Aguilar-Salinas, C.A., Akiyama, M., Allison, M.A., Alver, M., Aung, T., Azizi, F., Bentley, A.R., Boeing, H., Boerwinkle, E., Borja, J.B., de Borst, G.J., Bottinger, E.P., Broer, L., Campbell, H., Chanock, S., Chee, M.L., Chen, G., Chen, Y.D.I., Chen, Z., Chiu, Y.-F., Cocca, M., Collins, F.S., Concas, M.P., Corley, J., Cugliari, G., van Dam, R.M., Damulina, A., Daneshpour, M.S., Day, F.R., Delgado, G.E., Dhana, K., Doney, A.F.S., Dorr, M., Doumatey, A.P., Dzimiri, N., Ebenesersdottir, S.S., Elliott, J., Elliott, P., Ewert, R., Felix, J.F., Fischer, K., Freedman, B.I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M.O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D.F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S.P., Haiman, C.A., Halevy, A., Harris, T.B., Hedayati, M., van Heel, D.a., Hirata, M., Höfer, I., Hsiung, C.A., Huang, J., Hung, Y.-J., Ikram, M.A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N.D., Kessler, T., Khaw, K.-T., Khor, C.C., de Kleijn, D.P.V., Koh, W.-P., Kolcic, I., Kraft, P., Krämer, B.K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L.J., Lawlor, D.A., Lee, I.-T., Lee, W.-J., Lerch, M.M., Li, L., Liu, J., Loh, M., London, S.J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A.W., Manunta, P., Masson, G., Matoba, N., Mei, X.W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I.Y., Momozawa, Y., Moore, A., Morange, P.-E., Moreno-Macias, H., Mori, T.A., Morrison, A.C., Muka, T., Murakami, Y., Murray, a.D., de Mutsert, R., Mychaleckyj, J.C., Nalls, M.A., Nauck, M., Neville, M.J., Nolte, I.M., Ong, K.K., Orozco, L., Padmanabhan, S., Palsson, G., Pankow, J.S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P.P., Quintana-Murci, L, Räikkönen, K., Ralhan, S., Rao, D.C., van Rheenen, W., Rich, S.S., Ridker, P.M., Rietveld, C.A., Robino, A., van Rooij, F.J.A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C.F., Salomaa, V, Sandow, K., Schmidt, H., Scott, L.J., Scott, W.R., Sedaghati-Khayat, S., Sennblad, B., van Setter, J., Sever, P.J., Sheu, W.H.-H., Shi, Y., Shrestha, S., Shukla, S.R., Sigurdsson, J.K., Sikka, T.T., Singh, J.R., Smith, B.H., Stancakova, A, Stanton, A., Starr, J.M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M.A., Taylor, A.M., Taylor, K.D., Terzikhan, N., Tham, Y.-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R.P., Tusie-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J.H., Vitart V., Völker, U., Vuoksimaa, E., Wakil, S.M., Waldenberger, M., Wander, G.S., Wang, Y.X., Wareham, N.J., Wild, S., Yajnik, C.S., Yuan, J.-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F.W., Bakker, S.J.L., Becker, D.M., Lehne, B., Bennett, D.A., van den Berg, L.H., Berndt, S.I., Bharadwaj, D., Bielak, L.F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J.P., Brody, J.A., Campbell, A., Carmi, S., Caulfield, M.J., Cesarini, D., Chambers, J.C., Chandak, G.R., Cheng, C.-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G.D., Deary, I.J., Dorajoo, R., van Duijn, C.M., Ellinghaus, D., Erdmann, J., Eriksson, J.G., Evangelou, E, Evans, M.K., Faul, J.D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S.F.A, Griffiths, L., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C.-K., Hicks, A.A., Hochner, H., Huikuri, H., Hunt, S.C., Jaddoe, V.W.V., De Jager, P.L., Johannesson, M., Johansson, Å., Jonas, J.B., Jukema, J.W., Junttila, J., Kaprio, J., Kardia, S.L.R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S.W., Lahti, J., Laudes, M., Lea, R.A., Lieb, W., Lumley, T., Martin, N.G., März, W., Matullo, G., McCarthy, M.I., Medland, S.E., Merriman, T.R., Metspalu, A., Meyer, B.F., Mohlke, K.L., Montogomery, G.W., Mook-Kanamori, D., Munroe, P.B., North, K.E., Nyholt, D.R., O’Connell, J.R., Ober, C., Oldehinkel, A.J., Palmas, W., Palmer, C., Pasterkamp, G.G., Patin, E., Pennell, C.G., Perusse, L., Peyser, P.A., Pirastu, M., Polderman, T.J.C., Porteous, D.J., Posthuma, D., Psaty, B.M., Rioux, J.D., Rivadeneira, F., Rotimi, C., Rotter, J.I., Rudan, I, Den Ruijter, H.M., Sanghera, D.K., Sattar, N., Schmidt, R., Schulze, M.B., Schunkert, H., Scott, R.A., Shuldiner, A.R., Sim, X., Small, Neil A., Smith, J.A., Sotoodehnia, N., Tai, E.-S., Teumer, A., Timpson, N.J., Toniolo, D., Tregouet, D.-A., Tuomi, T., Vollenweider, P., Wang, C.A., Weir, D.R., Whitfield, J.B., Wijmenga C., Wng, T.-Y., Wright, J., Yang, J., Yu, L., Zemel, B.S., Zonderman, A.B., Perola, M., Magnusson, P.K.E., Uitterlinden, A.G., Kooner, J.S., Chasman, D.I., Loos, R.J.F., Franceschini, N., Franke, L., Haley, C.S., Hayward, C., Walters, R.G., Perry, J.R.B., Esko, T., Helgason, A., Stefansson, K., Joshi, P.K., Kubo, M., Wilson, J.F. |
| Publication Status: |
Published version |
| Rok vydání: |
2019 |
| Sbírka: |
Bradford Scholars |
| Original Material: |
Clark DW, Okada Y, Moore KHS, et al. (2019) Associations of autozygosity with a broad range of human phenotypes. Nature Communications. 10(1): 4957 |
| Témata: |
Consanguinity, Genetic association study, Genetic markers, Inbreeding, Inbreeding depression |
| Popis: |
Yes
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. Here, using genomic inbreeding coefficients (FROH) for >1.4 million individuals, we show that FROH is significantly associated (p |
| Original Identifier: |
oai:bradscholars.brad.ac.uk:10454/18210 |
| Druh dokumentu: |
Article |
| Jazyk: |
English |
| DOI: |
10.1038/s41467-019-12283-6 |
| Dostupnost: |
http://hdl.handle.net/10454/18210 |
| Rights: |
© 2019, The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License.
CC-BY |
| Přístupové číslo: |
edsndl.BRADFORD.oai.bradscholars.brad.ac.uk.10454.18210 |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
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