Association of restless legs syndrome and obesity: A sub-population of the MASHAD cohort study

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Názov: Association of restless legs syndrome and obesity: A sub-population of the MASHAD cohort study
Autori: Azam Vafaei, Fatemeh Khorashadizadeh, Maryam Saberi-Karimian, Sara Saffar Soflaei, Mahnaz Amini, Abolfazl Rashid, Sara Yousefian, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan, Reza Salaran, Fatemeh Taherian
Zdroj: Neurobiology of Sleep and Circadian Rhythms, Vol 18, Iss , Pp 100113- (2025)
Informácie o vydavateľovi: Elsevier, 2025.
Rok vydania: 2025
Zbierka: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
LCC:Biology (General)
Predmety: Restless legs syndrome, Body mass index, Waist circumference, Hip circumference, Waist to hip ratio, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Biology (General), QH301-705.5
Popis: Introduction: Restless Legs Syndrome (RLS), as a relatively unknown sleep disorder, often associated with obesity. The purpose of this study was to examine the relationship between RLS and different definitions of obesity within the Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study population. Methods: A total of 1006 subjects, with an average age of 57 (51.75–63.00) years old, were randomly selected from the MASHAD cohort study phase II. This sample included 449 males and 557 females, who were contacted by phone to inquire about RLS. Anthropometric measurements such as weight, height, waist circumference (WC), and hip circumference (HC) were taken. Central obesity was defined as a WC > 90 cm for men and >85 cm for women, as well as a waist-to-hip ratio (WHR) greater than 0.90 for men and 0.85 for women. Statistical analyses were conducted using R version 4.3.2 for Windows, with a significance level set at a two-sided P-value30 kg/m2 increased to 1.50(1.10–2.03) after adjusting for confounding factors (p-value30 kg/m2 increased odds of RLS by 1.72 times in males (95%CI: 1.03–2.84, p-value30 kg/m2 increased the odds of RLS by 1.50 times in the study population.
Druh dokumentu: article
Popis súboru: electronic resource
Jazyk: English
ISSN: 2451-9944
Relation: http://www.sciencedirect.com/science/article/pii/S2451994425000021; https://doaj.org/toc/2451-9944
DOI: 10.1016/j.nbscr.2025.100113
Prístupová URL adresa: https://doaj.org/article/eb73c470c52747d9bc6376036b48fbcf
Prístupové číslo: edsdoj.b73c470c52747d9bc6376036b48fbcf
Databáza: Directory of Open Access Journals
Popis
Abstrakt:Introduction: Restless Legs Syndrome (RLS), as a relatively unknown sleep disorder, often associated with obesity. The purpose of this study was to examine the relationship between RLS and different definitions of obesity within the Mashhad stroke and heart atherosclerotic disorder (MASHAD) cohort study population. Methods: A total of 1006 subjects, with an average age of 57 (51.75–63.00) years old, were randomly selected from the MASHAD cohort study phase II. This sample included 449 males and 557 females, who were contacted by phone to inquire about RLS. Anthropometric measurements such as weight, height, waist circumference (WC), and hip circumference (HC) were taken. Central obesity was defined as a WC > 90 cm for men and >85 cm for women, as well as a waist-to-hip ratio (WHR) greater than 0.90 for men and 0.85 for women. Statistical analyses were conducted using R version 4.3.2 for Windows, with a significance level set at a two-sided P-value30 kg/m2 increased to 1.50(1.10–2.03) after adjusting for confounding factors (p-value30 kg/m2 increased odds of RLS by 1.72 times in males (95%CI: 1.03–2.84, p-value30 kg/m2 increased the odds of RLS by 1.50 times in the study population.
ISSN:24519944
DOI:10.1016/j.nbscr.2025.100113