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Diet quality and nutrient distribution while using glucagon-like-peptide-1 receptor agonist: A secondary cross-sectional analysis

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Bibliographic Details
Title: Diet quality and nutrient distribution while using glucagon-like-peptide-1 receptor agonist: A secondary cross-sectional analysis
Authors: Brittany V.B. Johnson, Mary Milstead, Lauren Green, Rachel Kreider, Rachel Jones
Source: Obesity Pillars, Vol 16, Iss , Pp 100195- (2025)
Publisher Information: Elsevier, 2025.
Publication Year: 2025
Collection: LCC:Nutrition. Foods and food supply
LCC:Medicine
Subject Terms: Healthy eating index, Nutrient timing, Weight reduction, Obesity, Nutrient intake, Glucagon-like peptide-1 receptor agonists, Nutrition. Foods and food supply, TX341-641, Medicine
Description: Background: With the rise of glucagon-like-peptide-1 receptor agonist medications (GLP-1RA) for obesity treatment, understanding diet quality can be a valuable tool for providing evidence-based nutrition guidance. However, there is limited data on dietary intake during GLP-1RA treatment. Thus, we analyzed diet quality and nutrient timing while using GLP-1RA. Methods: This was a secondary analysis from a previous cross-sectional online survey questionnaire study involving adults currently using GLP-1RA for weight reduction (N = 69, 49.6 ± 12.3 years old, 35.9 ± 9.1 kg/m2). Three-day food records were analyzed using the Healthy Eating Index (HEI), a validated score that indicates overall diet quality. The 13 HEI components were scored from average 3-day food records and calculated using 95 % confidence intervals (CI). A Bonferroni correction applied significance accepted at p = 0.0038. Additionally, 95 % CI were calculated for calories, macronutrients, and fiber intake reported for breakfast, lunch, dinner, and snacks. Results: A 95 % CI revealed a total HEI score of 54 ± 12 (51.4, 57.3), significantly below the HEI goal (p
Document Type: article
File Description: electronic resource
Language: English
ISSN: 2667-3681
Relation: http://www.sciencedirect.com/science/article/pii/S2667368125000397; https://doaj.org/toc/2667-3681
DOI: 10.1016/j.obpill.2025.100195
Access URL: https://doaj.org/article/b2c00d28e2f5451e9fd02b5b058830ce
Accession Number: edsdoj.b2c00d28e2f5451e9fd02b5b058830ce
Database: Directory of Open Access Journals
Description
Abstract:Background: With the rise of glucagon-like-peptide-1 receptor agonist medications (GLP-1RA) for obesity treatment, understanding diet quality can be a valuable tool for providing evidence-based nutrition guidance. However, there is limited data on dietary intake during GLP-1RA treatment. Thus, we analyzed diet quality and nutrient timing while using GLP-1RA. Methods: This was a secondary analysis from a previous cross-sectional online survey questionnaire study involving adults currently using GLP-1RA for weight reduction (N = 69, 49.6 ± 12.3 years old, 35.9 ± 9.1 kg/m2). Three-day food records were analyzed using the Healthy Eating Index (HEI), a validated score that indicates overall diet quality. The 13 HEI components were scored from average 3-day food records and calculated using 95 % confidence intervals (CI). A Bonferroni correction applied significance accepted at p = 0.0038. Additionally, 95 % CI were calculated for calories, macronutrients, and fiber intake reported for breakfast, lunch, dinner, and snacks. Results: A 95 % CI revealed a total HEI score of 54 ± 12 (51.4, 57.3), significantly below the HEI goal (p
ISSN:26673681
DOI:10.1016/j.obpill.2025.100195