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Clinical Characteristics and Outcomes of a Cohort of Multiethnic Asian Patients with Cardiac Myxoma

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Název: Clinical Characteristics and Outcomes of a Cohort of Multiethnic Asian Patients with Cardiac Myxoma
Autoři: Irving Yu Le Shua, Pavarisa Tongboriboon, Faith Sim, Tony YW Li, Kian-Keong Poh, William KF Kong, Mark Y. Chan, Ping Chai, Tiong Cheng Yeo, Leonard LL Yeo, Benjamin YQ Tan, Hon Jen Wong, Yao Hao Teo, Ching-Hui Sia
Zdroj: Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)
Informace o vydavateli: Nature Portfolio, 2025.
Rok vydání: 2025
Sbírka: LCC:Medicine
LCC:Science
Témata: Asymptomatic, Cardiac myxoma, Cardiac surgery, Clinical characteristics, Major adverse cardiovascular events, Mortality, Medicine, Science
Popis: Abstract Cardiac myxomas are the most common primary cardiac tumours. The overall prevalence is very low and up to 25% present asymptomatically. In Asia, the data on myxomas is limited. Therefore, we aimed to outline a multi-ethnic Asian population of cardiac myxoma patients. We included all index echocardiographic diagnoses of myxoma at a tertiary cardiovascular referral centre from May 2004 to April 2021. A retrospective review of all patients’ medical records was conducted. Data including patient characteristics, clinical presentation, imaging, treatment, and outcomes were collected and analysed. A total of 64 patients (mean age 66.4 years old, male 61%) were diagnosed with cardiac myxoma. The incidence of major adverse cardiovascular events (MACE) was 10 (16.1%) and 10-year mortality was 11 (17.2%). The proportion of asymptomatic patients (30.2%) increased from 15.4% before 2012 to 35.3% after 2012. Pre-existing chronic kidney disease and ischaemic heart disease were independently associated with increased risk of mortality and MACE (p-values
Druh dokumentu: article
Popis souboru: electronic resource
Jazyk: English
ISSN: 2045-2322
Relation: https://doaj.org/toc/2045-2322
DOI: 10.1038/s41598-025-20863-4
Přístupová URL adresa: https://doaj.org/article/99e0baf565934938961b297e13b7e4fa
Přístupové číslo: edsdoj.99e0baf565934938961b297e13b7e4fa
Databáze: Directory of Open Access Journals
Popis
Abstrakt:Abstract Cardiac myxomas are the most common primary cardiac tumours. The overall prevalence is very low and up to 25% present asymptomatically. In Asia, the data on myxomas is limited. Therefore, we aimed to outline a multi-ethnic Asian population of cardiac myxoma patients. We included all index echocardiographic diagnoses of myxoma at a tertiary cardiovascular referral centre from May 2004 to April 2021. A retrospective review of all patients’ medical records was conducted. Data including patient characteristics, clinical presentation, imaging, treatment, and outcomes were collected and analysed. A total of 64 patients (mean age 66.4 years old, male 61%) were diagnosed with cardiac myxoma. The incidence of major adverse cardiovascular events (MACE) was 10 (16.1%) and 10-year mortality was 11 (17.2%). The proportion of asymptomatic patients (30.2%) increased from 15.4% before 2012 to 35.3% after 2012. Pre-existing chronic kidney disease and ischaemic heart disease were independently associated with increased risk of mortality and MACE (p-values
ISSN:20452322
DOI:10.1038/s41598-025-20863-4