Evaluating prevalence and consequence of residual disease in individuals with psoriasis receiving apremilast treatment: results from a US patient survey

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Bibliographic Details
Title: Evaluating prevalence and consequence of residual disease in individuals with psoriasis receiving apremilast treatment: results from a US patient survey
Authors: Tina Bhutani, Sayeli Jayade, Sanika Rege, Hannah Penton, Vardhaman Patel, Samaneh Kalirai, Daniel Wolin, Kimberly Boyle, Lauren Seigel
Source: Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Publisher Information: Taylor & Francis Group, 2024.
Publication Year: 2024
Collection: LCC:Dermatology
Subject Terms: Cross-sectional survey, humanistic burden, psoriasis therapy, Dermatology, RL1-803
Description: Purpose: This noninterventional, cross-sectional survey estimated the prevalence and consequences of residual disease in apremilast-treated US adults with moderate to severe psoriasis. Materials and Methods: Residual disease was defined as experiencing moderate, severe, or very severe psoriasis over the past week or having ≥3% body surface area affected, despite treatment. Factors associated with residual disease and its effects on flare-ups, humanistic burden, and health care resource utilization (HCRU) were evaluated. Results: Of the 344 apremilast users (mean age, 44.9 years; female, 65.4%), 174 (50.6%) had residual disease. It was more prevalent in Black versus White participants (OR, 4.5; 95% CI, 1.6–12.2), those receiving apremilast for ≥1 versus
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-1753
0954-6634
Relation: https://doaj.org/toc/0954-6634; https://doaj.org/toc/1471-1753
DOI: 10.1080/09546634.2024.2366532
Access URL: https://doaj.org/article/6a541e87403a42e39eeb760a48781c7a
Accession Number: edsdoj.6a541e87403a42e39eeb760a48781c7a
Database: Directory of Open Access Journals
Description
Abstract:Purpose: This noninterventional, cross-sectional survey estimated the prevalence and consequences of residual disease in apremilast-treated US adults with moderate to severe psoriasis. Materials and Methods: Residual disease was defined as experiencing moderate, severe, or very severe psoriasis over the past week or having ≥3% body surface area affected, despite treatment. Factors associated with residual disease and its effects on flare-ups, humanistic burden, and health care resource utilization (HCRU) were evaluated. Results: Of the 344 apremilast users (mean age, 44.9 years; female, 65.4%), 174 (50.6%) had residual disease. It was more prevalent in Black versus White participants (OR, 4.5; 95% CI, 1.6–12.2), those receiving apremilast for ≥1 versus
ISSN:14711753
09546634
DOI:10.1080/09546634.2024.2366532