Comparison of Prognostic Risk Models (IMDC, MSKCC, CFF) in Patients Diagnosed with Metastatic Renal Cell Cancer
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| Název: | Comparison of Prognostic Risk Models (IMDC, MSKCC, CFF) in Patients Diagnosed with Metastatic Renal Cell Cancer |
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| Autoři: | Merve KESKİNKILIÇ, Kübra CANASLAN, Hüseyin Salih SEMİZ, Tuğba YAVUZŞEN |
| Zdroj: | Forbes Tıp Dergisi, Vol 6, Iss 2, Pp 180-187 (2025) |
| Informace o vydavateli: | BUCA SEYFI DEMIRSOY TRAINING AND RESEARCH HOSPITAL, 2025. |
| Rok vydání: | 2025 |
| Sbírka: | LCC:Medicine (General) |
| Témata: | cleveland clinic foundation (ccf), international mrcc database consortium (imdc), memorial sloan kettering cancer center risk (mskcc), prognostic model, metastatic renal cell carcinoma (rcc), Medicine (General), R5-920 |
| Popis: | Objective: The aim of this study is to reveal the relationship and correlation between the International metastatic renal cell carcinoma (mRCC) Database Consortium (IMDC) and Memorial Sloan Kettering Cancer Center (MSKCC) risk models used to determine first-line treatment in metastatic mRCC and, less commonly, the Cleveland Clinic Foundation (CCF) prognostic risk model. Methods: The IMDC, MSKCC and CCF scores of mRCC patients who received immunotherapy (IO) and molecular targeted therapy were calculated retrospectively at the time of diagnosis.According to the score results, the patients were grouped as favorable,intermediate and poor risk.According to these risk groups,the median progression-free survival (mPFS) and median overall survival (mOS) of the patients were calculated and the correlation with each other was considered significant using appropriate statistical analyses, and p |
| Druh dokumentu: | article |
| Popis souboru: | electronic resource |
| Jazyk: | English Turkish |
| ISSN: | 2757-5241 |
| Relation: | https://doaj.org/toc/2757-5241 |
| DOI: | 10.4274/forbes.galenos.2025.78309 |
| Přístupová URL adresa: | https://doaj.org/article/56716632a5cc4d9faf1d56db1332c296 |
| Přístupové číslo: | edsdoj.56716632a5cc4d9faf1d56db1332c296 |
| Databáze: | Directory of Open Access Journals |
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Nájsť tento článok vo Web of Science | Abstrakt: | Objective: The aim of this study is to reveal the relationship and correlation between the International metastatic renal cell carcinoma (mRCC) Database Consortium (IMDC) and Memorial Sloan Kettering Cancer Center (MSKCC) risk models used to determine first-line treatment in metastatic mRCC and, less commonly, the Cleveland Clinic Foundation (CCF) prognostic risk model. Methods: The IMDC, MSKCC and CCF scores of mRCC patients who received immunotherapy (IO) and molecular targeted therapy were calculated retrospectively at the time of diagnosis.According to the score results, the patients were grouped as favorable,intermediate and poor risk.According to these risk groups,the median progression-free survival (mPFS) and median overall survival (mOS) of the patients were calculated and the correlation with each other was considered significant using appropriate statistical analyses, and p |
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| ISSN: | 27575241 |
| DOI: | 10.4274/forbes.galenos.2025.78309 |