View in EDS

Associations of relative muscular strength with blood pressure changes and incident hypertension: a prospective cohort study in Korea

Saved in:
Bibliographic Details
Title: Associations of relative muscular strength with blood pressure changes and incident hypertension: a prospective cohort study in Korea
Authors: Jae Ho Park, Joong-Yeon Lim, Hyun-Young Park
Source: BMC Public Health, Vol 25, Iss 1, Pp 1-10 (2025)
Publisher Information: BMC, 2025.
Publication Year: 2025
Collection: LCC:Public aspects of medicine
Subject Terms: Hypertension, Blood pressure, Muscular strength, Handgrip strength, Prevention, Public aspects of medicine, RA1-1270
Description: Abstract Background Hypertension is a chronic condition that increases the risk of incident cardiovascular disease and all-cause mortality. This study investigates the association between relative handgrip strength (rHGS), blood pressure (BP) changes, and incident hypertension risk. Methods Data from 25,103 hypertension-free participants from nationwide Korean cohorts at baseline were analyzed. Participants were categorized into sex-specific rHGS tertiles (low, mid, and high). Multiple linear regression models assessed the rHGS associations with annual BP changes, whereas multiple Cox proportional hazard regression models estimated incident hypertension risk. Results Over 105,833.68 person-years of follow-up, 3,401 (13.55%) participants developed hypertension. Every 0.1-unit increase in rHGS was associated with an annual decrease of 0.04 mmHg in systolic BP (SBP) and 0.02 mmHg in diastolic BP (DBP) among women. Women with mid and high rHGS had a 15% and 23% lower risk of hypertension, respectively, than those with low rHGS. In men, every 0.1-unit increase in rHGS was associated with an annual decrease of 0.02 mmHg in SBP; however, no significant association was observed between rHGS levels and incident hypertension risk. Conclusions Higher muscular strength may protect against hypertension, particularly in women. However, the observed annual SBP reduction with increasing rHGS in men and women suggests that higher muscular strength may improve BP.
Document Type: article
File Description: electronic resource
Language: English
ISSN: 1471-2458
Relation: https://doaj.org/toc/1471-2458
DOI: 10.1186/s12889-025-25091-z
Access URL: https://doaj.org/article/40b8d79485ca47cb8b12ebf34073ae4b
Accession Number: edsdoj.40b8d79485ca47cb8b12ebf34073ae4b
Database: Directory of Open Access Journals
Description
Abstract:Abstract Background Hypertension is a chronic condition that increases the risk of incident cardiovascular disease and all-cause mortality. This study investigates the association between relative handgrip strength (rHGS), blood pressure (BP) changes, and incident hypertension risk. Methods Data from 25,103 hypertension-free participants from nationwide Korean cohorts at baseline were analyzed. Participants were categorized into sex-specific rHGS tertiles (low, mid, and high). Multiple linear regression models assessed the rHGS associations with annual BP changes, whereas multiple Cox proportional hazard regression models estimated incident hypertension risk. Results Over 105,833.68 person-years of follow-up, 3,401 (13.55%) participants developed hypertension. Every 0.1-unit increase in rHGS was associated with an annual decrease of 0.04 mmHg in systolic BP (SBP) and 0.02 mmHg in diastolic BP (DBP) among women. Women with mid and high rHGS had a 15% and 23% lower risk of hypertension, respectively, than those with low rHGS. In men, every 0.1-unit increase in rHGS was associated with an annual decrease of 0.02 mmHg in SBP; however, no significant association was observed between rHGS levels and incident hypertension risk. Conclusions Higher muscular strength may protect against hypertension, particularly in women. However, the observed annual SBP reduction with increasing rHGS in men and women suggests that higher muscular strength may improve BP.
ISSN:14712458
DOI:10.1186/s12889-025-25091-z