Advances in the sustainable biosynthesis of valuable terpenoid flavor compounds and precursors in micro-organisms

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Název: Advances in the sustainable biosynthesis of valuable terpenoid flavor compounds and precursors in micro-organisms
Autoři: Qian Li, Yibo Ning, Deyu Liu, Jie Ren, Changtong Lu, Zhifei Chen, Guanglu Wang
Zdroj: Biotechnology for Biofuels and Bioproducts, Vol 18, Iss 1, Pp 1-21 (2025)
Informace o vydavateli: BMC, 2025.
Rok vydání: 2025
Sbírka: LCC:Biotechnology
LCC:Fuel
Témata: Terpenoids, Flavors and fragrances, Microbial cell factory, Biosynthetic strategy, Biotechnology, TP248.13-248.65, Fuel, TP315-360
Popis: Abstract Renowned for their distinctive aromas, terpenoid flavor compounds and their precursors are widely used in medicine, food, and the flavor and fragrance industries. Rapid advances in synthetic biology, including the modification of microbial chassis cells, the design of synthetic pathways for novel target products, and the integration of large-scale microbial fermentation, have enabled the development of microbial cell factories for the green and efficient production of terpenoid flavor compounds and their precursors, offering broader market potential. This review examines common biosynthetic mechanisms, recent progress in the field, and strategies for enhancing the biosynthetic efficiency of terpenoid flavor compounds and their precursors. This study aims to support the advancements of sustainable production technologies and promote industrial application within the flavor and fragrance sector.
Druh dokumentu: article
Popis souboru: electronic resource
Jazyk: English
ISSN: 2731-3654
Relation: https://doaj.org/toc/2731-3654
DOI: 10.1186/s13068-025-02699-2
Přístupová URL adresa: https://doaj.org/article/cedd32dc62394cb4bac4f3dbb0ce76b3
Přístupové číslo: edsdoj.32dc62394cb4bac4f3dbb0ce76b3
Databáze: Directory of Open Access Journals
Popis
Abstrakt:Abstract Renowned for their distinctive aromas, terpenoid flavor compounds and their precursors are widely used in medicine, food, and the flavor and fragrance industries. Rapid advances in synthetic biology, including the modification of microbial chassis cells, the design of synthetic pathways for novel target products, and the integration of large-scale microbial fermentation, have enabled the development of microbial cell factories for the green and efficient production of terpenoid flavor compounds and their precursors, offering broader market potential. This review examines common biosynthetic mechanisms, recent progress in the field, and strategies for enhancing the biosynthetic efficiency of terpenoid flavor compounds and their precursors. This study aims to support the advancements of sustainable production technologies and promote industrial application within the flavor and fragrance sector.
ISSN:27313654
DOI:10.1186/s13068-025-02699-2