Executive functions deficit in mild cognitive impairment. ; : Executive functions deficit in MCI
Uložené v:
| Názov: | Executive functions deficit in mild cognitive impairment. ; : Executive functions deficit in MCI |
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| Autori: | Traykov, Latchezar, Raoux, Nadine, Latour, Florence, Gallo, Livia, Hanon, Olivier, Baudic, Sophie, Bayle, Catherine, Wenisch, Emilie, Remy, Philippe, Rigaud, Anne-Sophie |
| Prispievatelia: | Department of Neurology, University Hospital Alexandrovska, Service de neurologie Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Epidémiologie, santé publique et développement, Université Bordeaux Segalen - Bordeaux 2-Institut National de la Santé et de la Recherche Médicale (INSERM), AP-HP - Hôpital Cochin Broca Hôtel Dieu Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Départment of neurosciences, Università degli Studi di Padova = University of Padua (Unipd), Physiopathologie et Pharmacologie Clinique de la Douleur (LPPD), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Zdroj: | ISSN: 1543-3633 ; Cognitive and Behavioral Neurology ; https://inserm.hal.science/inserm-00180083 ; Cognitive and Behavioral Neurology, 2007, 20 (4), pp.219-24. ⟨10.1097/WNN.0b013e31815e6254⟩. |
| Informácie o vydavateľovi: | CCSD Lippincott, Williams & Wilkins |
| Rok vydania: | 2007 |
| Zbierka: | Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| Predmety: | Alzheimer's disease, Mild Cognitive Impairment, Neuropsychology, Attention, Executive functions, Memory, MESH: Aged, 80 and over, MESH: Male, MESH: Memory, Short-Term, MESH: Mental Recall, MESH: Neuropsychological Tests, MESH: Phonetics, MESH: Problem Solving, MESH: Psychometrics, MESH: Psychomotor Performance, MESH: Reference Values, MESH: Reproducibility of Results, MESH: Alzheimer Disease, MESH: Semantics, MESH: Amnesia, MESH: Anomia, MESH: Attention, MESH: Cognition Disorders, MESH: Early Diagnosis, MESH: Female, MESH: Humans, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie |
| Popis: | International audience ; OBJECTIVE: To investigate whether patients diagnosed with amnestic mild cognitive impairment (MCI) have also impairment in attention/executive functions, and therefore to clarify whether all subcomponents of executive control are equally affected in MCI. BACKGROUND: MCI refers to the transitional state between normal aging and dementia. Amnestic MCI is characterized by impaired episodic memory, although subtle impairment of executive functions has been noted on neuropsychologic tests. METHODS: We investigated 20 MCI patients and 20 normal controls using episodic memory, attention/executive functions, language, and praxis tests. RESULTS: MCI patients had significantly lower scores on all measures of the Free and Cued Selective Reminding Test (P<0.05 to 0.01) than controls. Furthermore, MCI had a greater number of perseverations (P<0.01) on Modified Card Sorting Test and the lowest performance on the Stroop Test (P<0.02). CONCLUSIONS: Our findings showed impairment in episodic memory performance in MCI as compared with that of controls. In addition, MCI patients had problems with response inhibition, switching, and cognitive flexibility, which encompass various aspects of executive functions. This suggests that MCI may be identified by using a more detailed procedure for the assessment of cognitive decline than the evaluation of memory alone. |
| Druh dokumentu: | article in journal/newspaper |
| Jazyk: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/18091070; PUBMED: 18091070 |
| DOI: | 10.1097/WNN.0b013e31815e6254 |
| Dostupnosť: | https://inserm.hal.science/inserm-00180083 https://inserm.hal.science/inserm-00180083v1/document https://inserm.hal.science/inserm-00180083v1/file/Latcho.pdf https://doi.org/10.1097/WNN.0b013e31815e6254 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| Prístupové číslo: | edsbas.EC90197C |
| Databáza: | BASE |
Nájsť tento článok vo Web of Science | Abstrakt: | International audience ; OBJECTIVE: To investigate whether patients diagnosed with amnestic mild cognitive impairment (MCI) have also impairment in attention/executive functions, and therefore to clarify whether all subcomponents of executive control are equally affected in MCI. BACKGROUND: MCI refers to the transitional state between normal aging and dementia. Amnestic MCI is characterized by impaired episodic memory, although subtle impairment of executive functions has been noted on neuropsychologic tests. METHODS: We investigated 20 MCI patients and 20 normal controls using episodic memory, attention/executive functions, language, and praxis tests. RESULTS: MCI patients had significantly lower scores on all measures of the Free and Cued Selective Reminding Test (P<0.05 to 0.01) than controls. Furthermore, MCI had a greater number of perseverations (P<0.01) on Modified Card Sorting Test and the lowest performance on the Stroop Test (P<0.02). CONCLUSIONS: Our findings showed impairment in episodic memory performance in MCI as compared with that of controls. In addition, MCI patients had problems with response inhibition, switching, and cognitive flexibility, which encompass various aspects of executive functions. This suggests that MCI may be identified by using a more detailed procedure for the assessment of cognitive decline than the evaluation of memory alone. |
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| DOI: | 10.1097/WNN.0b013e31815e6254 |