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Pseudomonas aeruginosa et maladie broncho-pulmonaire chronique obstructive [Pseudomonas aeruginosa in chronic obstructive pulmonary disease].

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Bibliographic Details
Title: Pseudomonas aeruginosa et maladie broncho-pulmonaire chronique obstructive [Pseudomonas aeruginosa in chronic obstructive pulmonary disease].
Authors: Wavre-Oberhänsli, A., Nicod, L.P.
Publication Year: 2025
Collection: Université de Lausanne (UNIL): Serval - Serveur académique lausannois
Subject Terms: Cohort Studies, Disease Progression, Humans, Prevalence, Pseudomonas Infections/complications, Pseudomonas Infections/epidemiology, Pseudomonas aeruginosa/isolation & purification, Pulmonary Disease, Chronic Obstructive/complications, Chronic Obstructive/microbiology, Sputum/microbiology, Survival Analysis
Description: The role of Pseudomonas aeruginosa isolated in sputum cultures from adults with obstructive chronic pulmonary disease (COPD) is not well known. However, this pathogen has many factors of virulence and is responsible for several clinical manifestations in this setting. Isolation of a new strain of Pseudomonas is associated with a significant risk of exacerbation of the COPD and its prevalence depends on the severity of the COPD. The role of Pseudomonas among patients with COPD apart from exacerbations is less clear, but it could be responsible for an ignition for the airways and progression for the disease. Currently, the relevance of a prophylactic antibiotic therapy has not yet been demonstrated in COPD holders of Pseudomonas.
Document Type: article in journal/newspaper
Language: French
Relation: Revue Médicale Suisse; 1660-9379[print], 1660-9379[linking]; https://iris.unil.ch/handle/iris/178432; serval:BIB_AA49E84852CA
Availability: https://iris.unil.ch/handle/iris/178432
Accession Number: edsbas.B698889C
Database: BASE
Description
Abstract:The role of Pseudomonas aeruginosa isolated in sputum cultures from adults with obstructive chronic pulmonary disease (COPD) is not well known. However, this pathogen has many factors of virulence and is responsible for several clinical manifestations in this setting. Isolation of a new strain of Pseudomonas is associated with a significant risk of exacerbation of the COPD and its prevalence depends on the severity of the COPD. The role of Pseudomonas among patients with COPD apart from exacerbations is less clear, but it could be responsible for an ignition for the airways and progression for the disease. Currently, the relevance of a prophylactic antibiotic therapy has not yet been demonstrated in COPD holders of Pseudomonas.