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Pseudomonas aeruginosa et maladie broncho-pulmonaire chronique obstructive [Pseudomonas aeruginosa in chronic obstructive pulmonary disease].

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Titel: Pseudomonas aeruginosa et maladie broncho-pulmonaire chronique obstructive [Pseudomonas aeruginosa in chronic obstructive pulmonary disease].
Autoren: Wavre-Oberhänsli, A., Nicod, L.P.
Publikationsjahr: 2025
Bestand: Université de Lausanne (UNIL): Serval - Serveur académique lausannois
Schlagwörter: Cohort Studies, Disease Progression, Humans, Prevalence, Pseudomonas Infections/complications, Pseudomonas Infections/epidemiology, Pseudomonas aeruginosa/isolation & purification, Pulmonary Disease, Chronic Obstructive/complications, Chronic Obstructive/microbiology, Sputum/microbiology, Survival Analysis
Beschreibung: The role of Pseudomonas aeruginosa isolated in sputum cultures from adults with obstructive chronic pulmonary disease (COPD) is not well known. However, this pathogen has many factors of virulence and is responsible for several clinical manifestations in this setting. Isolation of a new strain of Pseudomonas is associated with a significant risk of exacerbation of the COPD and its prevalence depends on the severity of the COPD. The role of Pseudomonas among patients with COPD apart from exacerbations is less clear, but it could be responsible for an ignition for the airways and progression for the disease. Currently, the relevance of a prophylactic antibiotic therapy has not yet been demonstrated in COPD holders of Pseudomonas.
Publikationsart: article in journal/newspaper
Sprache: French
Relation: Revue Médicale Suisse; 1660-9379[print], 1660-9379[linking]; https://iris.unil.ch/handle/iris/178432; serval:BIB_AA49E84852CA
Verfügbarkeit: https://iris.unil.ch/handle/iris/178432
Dokumentencode: edsbas.B698889C
Datenbank: BASE
Beschreibung
Abstract:The role of Pseudomonas aeruginosa isolated in sputum cultures from adults with obstructive chronic pulmonary disease (COPD) is not well known. However, this pathogen has many factors of virulence and is responsible for several clinical manifestations in this setting. Isolation of a new strain of Pseudomonas is associated with a significant risk of exacerbation of the COPD and its prevalence depends on the severity of the COPD. The role of Pseudomonas among patients with COPD apart from exacerbations is less clear, but it could be responsible for an ignition for the airways and progression for the disease. Currently, the relevance of a prophylactic antibiotic therapy has not yet been demonstrated in COPD holders of Pseudomonas.