Medication-Related Admissions Among Older Patients in a Danish Emergency Department:Prevalence, Preventability and Characterisation

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Titel: Medication-Related Admissions Among Older Patients in a Danish Emergency Department:Prevalence, Preventability and Characterisation
Autoren: Christensen, Louise Westberg Strejby, Dalhoff, Kim Peder, Iversen, Esben, Juul-Larsen, Helle Gybel, Rasmussen, Line Jee Hartmann, Andersen, Aino Leegaard, Andersen, Ove, Houlind, Morten Baltzer
Quelle: Christensen , L W S , Dalhoff , K P , Iversen , E , Juul-Larsen , H G , Rasmussen , L J H , Andersen , A L , Andersen , O & Houlind , M B 2025 , ' Medication-Related Admissions Among Older Patients in a Danish Emergency Department : Prevalence, Preventability and Characterisation ' , Basic & clinical pharmacology & toxicology , vol. 137 , no. 6 , e70132 . https://doi.org/10.1111/bcpt.70132
Publikationsjahr: 2025
Bestand: University of Copenhagen: Research / Forskning ved Københavns Universitet
Schlagwörter: Humans, Denmark/epidemiology, Emergency Service, Hospital/statistics & numerical data, Aged, Male, Female, 80 and over, Retrospective Studies, Prevalence, Patient Admission/statistics & numerical data, Drug-Related Side Effects and Adverse Reactions/epidemiology, Hospitalization/statistics & numerical data
Beschreibung: The prevalence of medication-related admissions (MRAs) among older medical patients admitted to Danish emergency departments (EDs) remains limited. We aimed to determine the prevalence of possibly medication-related admissions (PMRAs) in this population, assess their preventability and identify patient characteristics that distinguish between patients with and without a PMRA. This retrospective, exploratory, descriptive secondary analysis included acutely admitted older medical patients (≥ 65 years) from the ED of Copenhagen University Hospital Hvidovre, Denmark, between October 2018 and April 2021. PMRAs were initially assessed using the Assessment Tool for Hospital Admissions Related to Medications, followed by final classifications and preventability assessments by an experienced panel of pharmacists and a pharmacologist. Among 193 admissions, 31 (16.1%) were classified as PMRAs, and 15 (48.4%) and 11 (35.5%) of these were deemed potentially or definitely preventable, respectively. Untreated conditions (19.4%) and miscommunication (16.1%) were identified as the most common reasons for PMRAs. No specific patient characteristics reliably distinguished between patients with and without a PMRA. In conclusion, MRAs appear to be highly prevalent in Danish EDs, emphasising the need for improved identification and prevention strategies.
Publikationsart: article in journal/newspaper
Sprache: English
DOI: 10.1111/bcpt.70132
Verfügbarkeit: https://researchprofiles.ku.dk/da/publications/2b389e65-a3bc-4f0c-adc1-c69918fa575c
https://doi.org/10.1111/bcpt.70132
Rights: info:eu-repo/semantics/closedAccess
Dokumentencode: edsbas.AB768326
Datenbank: BASE
Beschreibung
Abstract:The prevalence of medication-related admissions (MRAs) among older medical patients admitted to Danish emergency departments (EDs) remains limited. We aimed to determine the prevalence of possibly medication-related admissions (PMRAs) in this population, assess their preventability and identify patient characteristics that distinguish between patients with and without a PMRA. This retrospective, exploratory, descriptive secondary analysis included acutely admitted older medical patients (≥ 65 years) from the ED of Copenhagen University Hospital Hvidovre, Denmark, between October 2018 and April 2021. PMRAs were initially assessed using the Assessment Tool for Hospital Admissions Related to Medications, followed by final classifications and preventability assessments by an experienced panel of pharmacists and a pharmacologist. Among 193 admissions, 31 (16.1%) were classified as PMRAs, and 15 (48.4%) and 11 (35.5%) of these were deemed potentially or definitely preventable, respectively. Untreated conditions (19.4%) and miscommunication (16.1%) were identified as the most common reasons for PMRAs. No specific patient characteristics reliably distinguished between patients with and without a PMRA. In conclusion, MRAs appear to be highly prevalent in Danish EDs, emphasising the need for improved identification and prevention strategies.
DOI:10.1111/bcpt.70132