Zobrazit v EDS

Derivation of Indices of Cognitive Change Among Hispanic Adults and Elders

Uloženo v:
Podrobná bibliografie
Název: Derivation of Indices of Cognitive Change Among Hispanic Adults and Elders
Autoři: Duff, Kevin, Miller, Justin B., Cobos, Kim, Rodrigues, Jessica, O'Bryant, Sid E., HABS-HD Team
Zdroj: JAMA Network Open
Informace o vydavateli: American Medical Association
Rok vydání: 2024
Sbírka: UNTHSC Scholarly Repository (University. of North Texas Health Science Center)
Témata: Hispanic or Latino / statistics & numerical data, Hispanic or Latino / psychology, Neuropsychological Tests / statistics & numerical data, Cognition
Popis: IMPORTANCE: Determining the influence of race and ethnicity on change in cognitive test performance has significant implications for clinical practice and research in populations at risk for Alzheimer disease. OBJECTIVE: To evaluate the significance of race and ethnicity in predicting longitudinal cognitive test performance and to develop models to support evidence-based practice. DESIGN, SETTING, AND PARTICIPANTS: This prognostic study included baseline and 24-month follow-up data that were obtained from the Health and Aging Brain Study-Health Disparities (HABS-HD) study, an ongoing longitudinal observational study of aging and dementia in a multiracial, multiethnic cohort. Participants included community-dwelling adults and elders living in the Dallas and Fort Worth metropolitan area who were Hispanic and non-Hispanic adults older than the age of 50 years and were cognitively unimpaired. EXPOSURE: The primary exposure of interest was time, measured in months. MAIN OUTCOMES AND MEASURES: Demographic variables included age, sex, education, and race and ethnicity. Cognitive domains included attention and working memory, processing speed, language, memory, and executive functioning. Linear regression models predicted follow-up performance from baseline performance and demographic variables for 13 commonly used neuropsychological tests. Follow-up testing was the primary outcome for all domains. Raw scores from 13 standardized tests were used for analyses. RESULTS: This study included 799 adults who were cognitively unimpaired (352 Hispanic individuals [44.1%]; 447 non-Hispanic individuals [55.9%]; 524 female [65.6%]; mean [SD] age, 65.4 [8.1] years). In the regression models, all 13 follow-up scores were significantly predicted from their respective baseline scores and demographic variables. Baseline performance and education were the most consistent predictors of follow-up scores, contributing to all 13 models. Age was significantly associated with follow-up in 11 models, and sex was significant in 5 models. Race ...
Druh dokumentu: article in journal/newspaper
Popis souboru: application/pdf
Jazyk: unknown
Relation: https://doi.org/10.1001/jamanetworkopen.2024.31180; https://hdl.handle.net/20.500.12503/32946
Dostupnost: https://hdl.handle.net/20.500.12503/32946
Rights: Attribution 4.0 International (CC BY 4.0 Deed) ; http://creativecommons.org/licenses/by/4.0/ ; © 2024 Duff K et al.
Přístupové číslo: edsbas.AB3A5166
Databáze: BASE
Popis
Abstrakt:IMPORTANCE: Determining the influence of race and ethnicity on change in cognitive test performance has significant implications for clinical practice and research in populations at risk for Alzheimer disease. OBJECTIVE: To evaluate the significance of race and ethnicity in predicting longitudinal cognitive test performance and to develop models to support evidence-based practice. DESIGN, SETTING, AND PARTICIPANTS: This prognostic study included baseline and 24-month follow-up data that were obtained from the Health and Aging Brain Study-Health Disparities (HABS-HD) study, an ongoing longitudinal observational study of aging and dementia in a multiracial, multiethnic cohort. Participants included community-dwelling adults and elders living in the Dallas and Fort Worth metropolitan area who were Hispanic and non-Hispanic adults older than the age of 50 years and were cognitively unimpaired. EXPOSURE: The primary exposure of interest was time, measured in months. MAIN OUTCOMES AND MEASURES: Demographic variables included age, sex, education, and race and ethnicity. Cognitive domains included attention and working memory, processing speed, language, memory, and executive functioning. Linear regression models predicted follow-up performance from baseline performance and demographic variables for 13 commonly used neuropsychological tests. Follow-up testing was the primary outcome for all domains. Raw scores from 13 standardized tests were used for analyses. RESULTS: This study included 799 adults who were cognitively unimpaired (352 Hispanic individuals [44.1%]; 447 non-Hispanic individuals [55.9%]; 524 female [65.6%]; mean [SD] age, 65.4 [8.1] years). In the regression models, all 13 follow-up scores were significantly predicted from their respective baseline scores and demographic variables. Baseline performance and education were the most consistent predictors of follow-up scores, contributing to all 13 models. Age was significantly associated with follow-up in 11 models, and sex was significant in 5 models. Race ...