The bioactive compounds, beneficial medicinal properties, and biotechnological prospects of Fomitopsis : a comprehensive overview

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Název: The bioactive compounds, beneficial medicinal properties, and biotechnological prospects of Fomitopsis : a comprehensive overview
Autoři: Karunarathna, Samantha C, Patabendige, Nimesha M, Kumla, Jaturong, Hapuarachchi, Kalani K, Suwannarach, Nakarin
Informace o vydavateli: Frontiers Media SA
Rok vydání: 2025
Témata: Anti-Infective Agents - chemistry, Anti-Infective Agents - pharmacology, Anti-Inflammatory Agents - pharmacology, Antineoplastic Agents - pharmacology, Antioxidants - chemistry, Antioxidants - pharmacology, Biological Products - chemistry, Biological Products - pharmacology, Biotechnology - methods, Coriolaceae - chemistry, Coriolaceae - metabolism, Humans, Immunologic Factors - pharmacology, Phenols - chemistry, Phenols - pharmacology, Polysaccharides - chemistry, Polysaccharides - pharmacology, Secondary Metabolism, Terpenes - chemistry, Terpenes - isolation & purification, Terpenes - pharmacology
Popis: Members of the genus Fomitopsis are medicinal mushrooms and a rich source of bioactive compounds with significant pharmacological and biotechnological potential. This paper provides a comprehensive review of their secondary metabolites, including polysaccharides, terpenoids, and phenolic compounds. In addition, their chemical structures and biological activities are described in detail. These compounds exhibit antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory properties, with promising applications in cancer therapy, cardiovascular health, and immune modulation. Beyond medicine, Fomitopsis plays a crucial role in biotechnology, contributing to bioremediation, biofuel production, pharmaceutical development, and functional food innovation. By integrating traditional medicinal knowledge with recent scientific advances, this review highlights the biomedical significance and industrial relevance of Fomitopsis, underscoring its expanding role in health and environmental sustainability.
Druh dokumentu: article in journal/newspaper
Popis souboru: pdf
Jazyk: English
Relation: ispartof: Frontiers in cellular and infection microbiology vol 15; WOS:001481434000001; 991005778129307891; https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12178400980007891/13178400970007891; alma:61MUN_INST/bibs/991005778129307891
DOI: 10.3389/fcimb.2025.1534617
Dostupnost: https://doi.org/10.3389/fcimb.2025.1534617
https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/The-bioactive-compounds-beneficial-medicinal-properties/991005778129307891
https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12178400980007891/13178400970007891
Rights: © 2025 Karunarathna et al. ; Open ; CC BY V4.0
Přístupové číslo: edsbas.8B77EC09
Databáze: BASE
Popis
Abstrakt:Members of the genus Fomitopsis are medicinal mushrooms and a rich source of bioactive compounds with significant pharmacological and biotechnological potential. This paper provides a comprehensive review of their secondary metabolites, including polysaccharides, terpenoids, and phenolic compounds. In addition, their chemical structures and biological activities are described in detail. These compounds exhibit antioxidant, antimicrobial, anti-inflammatory, and immunomodulatory properties, with promising applications in cancer therapy, cardiovascular health, and immune modulation. Beyond medicine, Fomitopsis plays a crucial role in biotechnology, contributing to bioremediation, biofuel production, pharmaceutical development, and functional food innovation. By integrating traditional medicinal knowledge with recent scientific advances, this review highlights the biomedical significance and industrial relevance of Fomitopsis, underscoring its expanding role in health and environmental sustainability.
DOI:10.3389/fcimb.2025.1534617