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Point-shear wave elastography predicts liver hypertrophy after portal vein embolization and postoperative liver failure.

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Název: Point-shear wave elastography predicts liver hypertrophy after portal vein embolization and postoperative liver failure.
Autoři: Hocquelet, A., Frulio, N., Gallo, G., Laurent, C., Papadopoulos, P., Salut, C., Denys, A., Trillaud, H.
Rok vydání: 2025
Sbírka: Université de Lausanne (UNIL): Serval - Serveur académique lausannois
Témata: Adult, Aged, 80 and over, Elasticity Imaging Techniques/methods, Embolization, Therapeutic/methods, Female, Humans, Hypertrophy, Liver/pathology, Liver Failure/diagnostic imaging, Liver Neoplasms/therapy, Male, Middle Aged, Portal Vein, Postoperative Complications/diagnostic imaging, Predictive Value of Tests, Retrospective Studies, Acoustic radiation force impulse (ARFI), Elastography, Point-share wave elastography (SWE), Portal vein embolization, Shear-wave velocity
Popis: To correlate point-shear wave elastography (SWE) with liver hypertrophy after right portal vein embolization (RPVE) and to determine its usefulness in predicting postoperative liver failure in patients undergoing partial liver resection. Point-SWE was performed the day before RPVE in 56 patients (41 men) with a median age of 66 years. The percentage (%) of future remnant liver (FRL) volume increase was defined as: %FRL post -%FRL pre %FRL pre ×100 and assessed on computed tomography performed 4 weeks after RPVE. Median (range) %FRL pre and %FRL post was respectively, 31.5% (12-48%) and 41% (23-61%) (P<0.001), with a median %FRL volume increase of 25.6% (-8; 123%). SWE correlated with %FRL volume increase (P=-0.510; P<0.001). SWV (P=0.003) and %FRL pre (P<0.001) were associated with %FRL volume increase at multivariate regression analysis. Forty-three patients (77%) were operated. Postoperative liver failure occurred in 14 patients (32.5%). Median SWE was different between the group with (1.68m/s) and without liver failure (1.07m/s) (P=0.018). The AUROC of SWE predicting liver failure was 0.724 with a best cut-off of 1.31m/s, corresponding to a sensitivity of 21%, specificity of 96%, positive predictive value 75% and negative predictive value of 72%. SWE was the single independent preoperative variable associated with liver failure. SWE assessed by point-SWE is a simple and useful tool to predict the FRL volume increase and postoperative liver failure in a population of patients with liver tumor.
Druh dokumentu: article in journal/newspaper
Jazyk: English
ISSN: 2211-5684
Relation: Diagnostic and Interventional Imaging; https://iris.unil.ch/handle/iris/235852; serval:BIB_DCAC71847F8E; 000434762800004
DOI: 10.1016/j.diii.2018.01.003
Dostupnost: https://iris.unil.ch/handle/iris/235852
https://doi.org/10.1016/j.diii.2018.01.003
Přístupové číslo: edsbas.68A6DACD
Databáze: BASE
Popis
Abstrakt:To correlate point-shear wave elastography (SWE) with liver hypertrophy after right portal vein embolization (RPVE) and to determine its usefulness in predicting postoperative liver failure in patients undergoing partial liver resection. Point-SWE was performed the day before RPVE in 56 patients (41 men) with a median age of 66 years. The percentage (%) of future remnant liver (FRL) volume increase was defined as: %FRL post -%FRL pre %FRL pre ×100 and assessed on computed tomography performed 4 weeks after RPVE. Median (range) %FRL pre and %FRL post was respectively, 31.5% (12-48%) and 41% (23-61%) (P<0.001), with a median %FRL volume increase of 25.6% (-8; 123%). SWE correlated with %FRL volume increase (P=-0.510; P<0.001). SWV (P=0.003) and %FRL pre (P<0.001) were associated with %FRL volume increase at multivariate regression analysis. Forty-three patients (77%) were operated. Postoperative liver failure occurred in 14 patients (32.5%). Median SWE was different between the group with (1.68m/s) and without liver failure (1.07m/s) (P=0.018). The AUROC of SWE predicting liver failure was 0.724 with a best cut-off of 1.31m/s, corresponding to a sensitivity of 21%, specificity of 96%, positive predictive value 75% and negative predictive value of 72%. SWE was the single independent preoperative variable associated with liver failure. SWE assessed by point-SWE is a simple and useful tool to predict the FRL volume increase and postoperative liver failure in a population of patients with liver tumor.
ISSN:22115684
DOI:10.1016/j.diii.2018.01.003