FRACTIONAL MATHEMATICAL MODEL OF HIV AND CD4+ T-CELLS INTERACTIONS WITH HAART TREATMENT

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Název: FRACTIONAL MATHEMATICAL MODEL OF HIV AND CD4+ T-CELLS INTERACTIONS WITH HAART TREATMENT
Autoři: Nisardi, Muhammad Rifki, Kasbawati, Kasbawati, Putra, Restu Ananda
Zdroj: Journal of Fundamental Mathematics and Applications (JFMA); Vol 6, No 1 (2023); 54-70 ; 2621-6035 ; 2621-6019
Informace o vydavateli: Diponegoro University
Rok vydání: 2023
Sbírka: Universitas Diponegoro: Undip E-Journal System (UEJS) Portal
Témata: HIV-Model, Fractional Order, Basic Reproduction Number, Grunwald-Letnikov Method
Popis: This study provides the mathematical model of the interaction between the HIV and CD4+ T cells. This research develops other research by formulating a model with the fractional Caputo derivative approach with fractional order α. Based on the model, we obtain the equilibrium point and analyze the stability criterion of the equilibrium point. Furthermore, we perform the Next Generation Matrix method to calculate the basic reproduction number. Then, we apply the Grunwald-Letnikov Explicit method to show the numerical result of the model.
Druh dokumentu: article in journal/newspaper
Popis souboru: application/pdf
Jazyk: Indonesian
Relation: https://ejournal2.undip.ac.id/index.php/jfma/article/view/17174/9623; https://ejournal2.undip.ac.id/index.php/jfma/article/view/17174
DOI: 10.14710/jfma.v6i1.17174
Dostupnost: https://ejournal2.undip.ac.id/index.php/jfma/article/view/17174
https://doi.org/10.14710/jfma.v6i1.17174
Rights: Copyright (c) 2023 Journal of Fundamental Mathematics and Applications (JFMA)
Přístupové číslo: edsbas.6240B143
Databáze: BASE
Popis
Abstrakt:This study provides the mathematical model of the interaction between the HIV and CD4+ T cells. This research develops other research by formulating a model with the fractional Caputo derivative approach with fractional order α. Based on the model, we obtain the equilibrium point and analyze the stability criterion of the equilibrium point. Furthermore, we perform the Next Generation Matrix method to calculate the basic reproduction number. Then, we apply the Grunwald-Letnikov Explicit method to show the numerical result of the model.
DOI:10.14710/jfma.v6i1.17174