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Individual treatment selection for patients with post-traumatic stress disorder: external validation of a personalised advantage index

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Názov: Individual treatment selection for patients with post-traumatic stress disorder: external validation of a personalised advantage index
Autori: Tait, J., Kellett, S., Saxon, D., Deisenhofer, A.-K., Lutz, W., Barkham, M., Delgadillo, J.
Informácie o vydavateľovi: Taylor & Francis
Rok vydania: 2025
Zbierka: White Rose Research Online (Universities of Leeds, Sheffield & York)
Popis: OBJECTIVE: To test the predictive accuracy and generalisability of a personalised advantage index (PAI) model designed to support treatment selection for Post-Traumatic Stress Disorder (PTSD). METHOD: A PAI model developed by Deisenhofer et al. (2018) was used to predict treatment outcomes in a statistically independent dataset including archival records for N = 152 patients with PSTD who accessed either trauma-focussed cognitive behavioural therapy or eye movement desensitisation and reprocessing in routine care. Outcomes were compared between patients who received their PAI-indicated optimal treatment versus those who received their suboptimal treatment. RESULTS: The model did not yield treatment specific predictions and patients who had received their PAI-indicated optimal treatment did not have better treatment outcomes in this external validation sample. CONCLUSION: This PAI model did not generalise to an external validation sample.
Druh dokumentu: article in journal/newspaper
Popis súboru: text
Jazyk: English
Relation: https://eprints.whiterose.ac.uk/id/eprint/213567/1/Individual%20treatment%20selection%20for%20patients%20with%20post-traumatic%20stress%20disorder%20%20External%20validation%20of%20a%20personalised%20advantage%20index.pdf; Tait, J. orcid.org/0000-0002-5336-0363 , Kellett, S. orcid.org/0000-0001-6034-4495 , Saxon, D. orcid.org/0000-0002-9753-8477 et al. (4 more authors) (2025) Individual treatment selection for patients with post-traumatic stress disorder: external validation of a personalised advantage index. Psychotherapy Research, 35 (5). pp. 838-851. ISSN: 1050-3307
Dostupnosť: https://eprints.whiterose.ac.uk/id/eprint/213567/
Rights: cc_by_4
Prístupové číslo: edsbas.43D696D2
Databáza: BASE
Popis
Abstrakt:OBJECTIVE: To test the predictive accuracy and generalisability of a personalised advantage index (PAI) model designed to support treatment selection for Post-Traumatic Stress Disorder (PTSD). METHOD: A PAI model developed by Deisenhofer et al. (2018) was used to predict treatment outcomes in a statistically independent dataset including archival records for N = 152 patients with PSTD who accessed either trauma-focussed cognitive behavioural therapy or eye movement desensitisation and reprocessing in routine care. Outcomes were compared between patients who received their PAI-indicated optimal treatment versus those who received their suboptimal treatment. RESULTS: The model did not yield treatment specific predictions and patients who had received their PAI-indicated optimal treatment did not have better treatment outcomes in this external validation sample. CONCLUSION: This PAI model did not generalise to an external validation sample.