Tobacco smoking and oral clefts: a meta-analysis
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| Názov: | Tobacco smoking and oral clefts: a meta-analysis |
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| Autori: | Julian Little, A. H. Cardy, Ronald G. Munger |
| Zdroj: | Bulletin of the World Health Organization, Vol 82, Iss 3, Pp 213-218 (2004) |
| Informácie o vydavateľovi: | The World Health Organization, 2004. |
| Rok vydania: | 2004 |
| Predmety: | Cleft lip/epidemiology, Dose-response relationship, Cleft palate/epidemiology, Cleft Lip, Case-control studies, Global Health, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Smoking/adverse effects, Humans, Dose-Response Relationship, Drug, Smoking, Cleft lip/etiology, Infant, Newborn, Infant, Tobacco Products, Newborn, 3. Good health, Cleft Palate, Meta-analysis, Cleft palate/etiology, Case-Control Studies, Cohort studies, Female, Drug, Public aspects of medicine, RA1-1270 |
| Popis: | To examine the association between maternal smoking and non-syndromic orofacial clefts in infants.A meta-analysis of the association between maternal smoking during pregnancy was carried out using data from 24 case-control and cohort studies.Consistent, moderate and statistically significant associations were found between maternal smoking and cleft lip, with or without cleft palate (relative risk 1.34, 95% confidence interval 1.25-1.44) and between maternal smoking and cleft palate (relative risk 1.22, 95% confidence interval 1.10-1.35). There was evidence of a modest dose-response effect for cleft lip with or without cleft palate.The evidence of an association between maternal tobacco smoking and orofacial clefts is strong enough to justify its use in anti-smoking campaigns. |
| Druh dokumentu: | Article |
| Jazyk: | English |
| ISSN: | 0042-9686 |
| DOI: | 10.1590/s0042-96862004000300011 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/15112010 https://doaj.org/article/0f3031c0b60642c8960a8f1d2d3a7ade https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585921/ http://europepmc.org/articles/PMC2585921 https://abdn.pure.elsevier.com/en/publications/tobacco-smoking-and-oral-clefts-a-meta-analysis https://www.scielosp.org/article/ssm/content/raw/?resource_ssm_path=/media/assets/bwho/v82n3/v82n3a11.pdf https://www.who.int/entity/bulletin/volumes/82/3/en/213-218.pdf https://www.scielosp.org/article/bwho/2004.v82n3/213-218/en/ |
| Prístupové číslo: | edsair.pmid.dedup....f87c031f3d75f7ff1fc19fc7dbd4aadf |
| Databáza: | OpenAIRE |
| Abstrakt: | To examine the association between maternal smoking and non-syndromic orofacial clefts in infants.A meta-analysis of the association between maternal smoking during pregnancy was carried out using data from 24 case-control and cohort studies.Consistent, moderate and statistically significant associations were found between maternal smoking and cleft lip, with or without cleft palate (relative risk 1.34, 95% confidence interval 1.25-1.44) and between maternal smoking and cleft palate (relative risk 1.22, 95% confidence interval 1.10-1.35). There was evidence of a modest dose-response effect for cleft lip with or without cleft palate.The evidence of an association between maternal tobacco smoking and orofacial clefts is strong enough to justify its use in anti-smoking campaigns. |
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| ISSN: | 00429686 |
| DOI: | 10.1590/s0042-96862004000300011 |
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