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Dilemma’s rond lymfadenopathie na covid-19-vaccinatie

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Title: Dilemma’s rond lymfadenopathie na covid-19-vaccinatie
Authors: Davidson, Linda, van Nieuwkoop, Cees, Platteel, Tamara N, Kartachova, Marina S, Kant, Agnes C, van Hunsel, Florence P A M
Source: Nederlands Tijdschrift voor Geneeskunde. 169
Publisher Information: NLM (Medline), 2025.
Publication Year: 2025
Subject Terms: Lymphadenopathy/etiology, Time Factors, SARS-CoV-2, COVID-19/prevention & control, Humans, Vaccination/adverse effects, Female, COVID-19 Vaccines/adverse effects
Description: Reactive lymphadenopathy after COVID-19 vaccination occurs frequently and usually recovers within 1-2 weeks. It can, however, persist for more than six months in some cases. Axillary lymphadenopathy at the site of vaccination is most common. Cervical and supraclavicular lymphadenopathy is also reported. A wait-and-see approach for 2-3 weeks seems justified when time between onset of lymphadenopathy and covid-19 vaccination is several days to weeks, there is no progression, lymphadenopathy is unilateral and localised axillary or cervical in patients without a history of malignancy and without alarm symptoms. In cases of persistent lymphadenopathy, ultrasound of the affected lymph node is recommended. In cases of unilateral axillary lymphadenopathy in women, breast examination with mammography and/or breast ultrasound is also warranted. In the absence of any abnormalities referral to secondary care can be delayed for 8-12 weeks. After this time period we advise referral to secondary care to exclude any underlying illness.
Document Type: Article
Language: Dutch; Flemish
ISSN: 1876-8784
0028-2162
Access URL: https://research.rug.nl/en/publications/c04c5204-0d93-4c7a-9d3f-5393581da89b
https://hdl.handle.net/11370/c04c5204-0d93-4c7a-9d3f-5393581da89b
Accession Number: edsair.dris...01423..f903968610c36d8bbbdce66e62a4f493
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  Data: Dilemma’s rond lymfadenopathie na covid-19-vaccinatie
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  Data: <searchLink fieldCode="AR" term="%22Davidson%2C+Linda%22">Davidson, Linda</searchLink><br /><searchLink fieldCode="AR" term="%22van+Nieuwkoop%2C+Cees%22">van Nieuwkoop, Cees</searchLink><br /><searchLink fieldCode="AR" term="%22Platteel%2C+Tamara+N%22">Platteel, Tamara N</searchLink><br /><searchLink fieldCode="AR" term="%22Kartachova%2C+Marina+S%22">Kartachova, Marina S</searchLink><br /><searchLink fieldCode="AR" term="%22Kant%2C+Agnes+C%22">Kant, Agnes C</searchLink><br /><searchLink fieldCode="AR" term="%22van+Hunsel%2C+Florence+P+A+M%22">van Hunsel, Florence P A M</searchLink>
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  Data: <i>Nederlands Tijdschrift voor Geneeskunde</i>. 169
– Name: Publisher
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  Data: NLM (Medline), 2025.
– Name: DatePubCY
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  Data: 2025
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  Data: <searchLink fieldCode="DE" term="%22Lymphadenopathy%2Fetiology%22">Lymphadenopathy/etiology</searchLink><br /><searchLink fieldCode="DE" term="%22Time+Factors%22">Time Factors</searchLink><br /><searchLink fieldCode="DE" term="%22SARS-CoV-2%22">SARS-CoV-2</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19%2Fprevention+%26+control%22">COVID-19/prevention & control</searchLink><br /><searchLink fieldCode="DE" term="%22Humans%22">Humans</searchLink><br /><searchLink fieldCode="DE" term="%22Vaccination%2Fadverse+effects%22">Vaccination/adverse effects</searchLink><br /><searchLink fieldCode="DE" term="%22Female%22">Female</searchLink><br /><searchLink fieldCode="DE" term="%22COVID-19+Vaccines%2Fadverse+effects%22">COVID-19 Vaccines/adverse effects</searchLink>
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Reactive lymphadenopathy after COVID-19 vaccination occurs frequently and usually recovers within 1-2 weeks. It can, however, persist for more than six months in some cases. Axillary lymphadenopathy at the site of vaccination is most common. Cervical and supraclavicular lymphadenopathy is also reported. A wait-and-see approach for 2-3 weeks seems justified when time between onset of lymphadenopathy and covid-19 vaccination is several days to weeks, there is no progression, lymphadenopathy is unilateral and localised axillary or cervical in patients without a history of malignancy and without alarm symptoms. In cases of persistent lymphadenopathy, ultrasound of the affected lymph node is recommended. In cases of unilateral axillary lymphadenopathy in women, breast examination with mammography and/or breast ultrasound is also warranted. In the absence of any abnormalities referral to secondary care can be delayed for 8-12 weeks. After this time period we advise referral to secondary care to exclude any underlying illness.
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    Languages:
      – Text: Dutch; Flemish
    Subjects:
      – SubjectFull: Lymphadenopathy/etiology
        Type: general
      – SubjectFull: Time Factors
        Type: general
      – SubjectFull: SARS-CoV-2
        Type: general
      – SubjectFull: COVID-19/prevention & control
        Type: general
      – SubjectFull: Humans
        Type: general
      – SubjectFull: Vaccination/adverse effects
        Type: general
      – SubjectFull: Female
        Type: general
      – SubjectFull: COVID-19 Vaccines/adverse effects
        Type: general
    Titles:
      – TitleFull: Dilemma’s rond lymfadenopathie na covid-19-vaccinatie
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            NameFull: Davidson, Linda
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            NameFull: van Nieuwkoop, Cees
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            NameFull: Platteel, Tamara N
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            NameFull: Kartachova, Marina S
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            NameFull: Kant, Agnes C
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            NameFull: van Hunsel, Florence P A M
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            – D: 25
              M: 08
              Type: published
              Y: 2025
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