Dilemma’s rond lymfadenopathie na covid-19-vaccinatie

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Bibliographic Details
Title: Dilemma’s rond lymfadenopathie na covid-19-vaccinatie
Authors: Davidson, Linda, van Nieuwkoop, Cees, Platteel, Tamara N, Kartachova, Marina S, Kant, Agnes C, van Hunsel, Florence P A M
Source: Nederlands Tijdschrift voor Geneeskunde. 169
Publisher Information: NLM (Medline), 2025.
Publication Year: 2025
Subject Terms: Lymphadenopathy/etiology, Time Factors, SARS-CoV-2, COVID-19/prevention & control, Humans, Vaccination/adverse effects, Female, COVID-19 Vaccines/adverse effects
Description: Reactive lymphadenopathy after COVID-19 vaccination occurs frequently and usually recovers within 1-2 weeks. It can, however, persist for more than six months in some cases. Axillary lymphadenopathy at the site of vaccination is most common. Cervical and supraclavicular lymphadenopathy is also reported. A wait-and-see approach for 2-3 weeks seems justified when time between onset of lymphadenopathy and covid-19 vaccination is several days to weeks, there is no progression, lymphadenopathy is unilateral and localised axillary or cervical in patients without a history of malignancy and without alarm symptoms. In cases of persistent lymphadenopathy, ultrasound of the affected lymph node is recommended. In cases of unilateral axillary lymphadenopathy in women, breast examination with mammography and/or breast ultrasound is also warranted. In the absence of any abnormalities referral to secondary care can be delayed for 8-12 weeks. After this time period we advise referral to secondary care to exclude any underlying illness.
Document Type: Article
Language: Dutch; Flemish
ISSN: 1876-8784
0028-2162
Access URL: https://research.rug.nl/en/publications/c04c5204-0d93-4c7a-9d3f-5393581da89b
https://hdl.handle.net/11370/c04c5204-0d93-4c7a-9d3f-5393581da89b
Accession Number: edsair.dris...01423..f903968610c36d8bbbdce66e62a4f493
Database: OpenAIRE
Description
Abstract:Reactive lymphadenopathy after COVID-19 vaccination occurs frequently and usually recovers within 1-2 weeks. It can, however, persist for more than six months in some cases. Axillary lymphadenopathy at the site of vaccination is most common. Cervical and supraclavicular lymphadenopathy is also reported. A wait-and-see approach for 2-3 weeks seems justified when time between onset of lymphadenopathy and covid-19 vaccination is several days to weeks, there is no progression, lymphadenopathy is unilateral and localised axillary or cervical in patients without a history of malignancy and without alarm symptoms. In cases of persistent lymphadenopathy, ultrasound of the affected lymph node is recommended. In cases of unilateral axillary lymphadenopathy in women, breast examination with mammography and/or breast ultrasound is also warranted. In the absence of any abnormalities referral to secondary care can be delayed for 8-12 weeks. After this time period we advise referral to secondary care to exclude any underlying illness.
ISSN:18768784
00282162