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Perioperative antibiotic prophylaxis in the setting of cochlear implantation: a retrospective analysis of 700 cases

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Název: Perioperative antibiotic prophylaxis in the setting of cochlear implantation: a retrospective analysis of 700 cases
Autoři: Katharina Schaumann, D. Mütz, L. Althaus, T. Prinzen, J. Schipper, T. Klenzner
Zdroj: Eur Arch Otorhinolaryngol
Informace o vydavateli: Springer Science and Business Media LLC, 2024.
Rok vydání: 2024
Témata: Male, Adult, Adolescent, Infant, Otology, Antibiotic Prophylaxis, Middle Aged, Cochlear Implantation, Perioperative Care, Anti-Bacterial Agents, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Child, Preschool, Aged [MeSH], Cochlear Implantation/adverse effects [MeSH], Surgical Wound Infection/epidemiology [MeSH], Anti-Bacterial Agents/administration, Infant [MeSH], Male [MeSH], Revision surgery, Child [MeSH], Perioperative antibiotic prophylaxis, Surgical Wound Infection/prevention, Adolescent [MeSH], Female [MeSH], Anti-Bacterial Agents/therapeutic use [MeSH], Adult [MeSH], Explantation, Humans [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Perioperative Care/methods [MeSH], Wound infection, Cochlear implantation, Young Adult [MeSH], Surgical site infection, Antibiotic Prophylaxis/methods [MeSH], Child, Preschool [MeSH], Humans, Surgical Wound Infection, Female, Child, Retrospective Studies, Aged
Popis: Purpose Postoperative wound infections after cochlear implantation are rare but sometimes serious and can lead to explantation. Therefore, perioperative antibiotic administration is often recommended. However, in clinical practice, the type and duration of antibiotic prophylaxis varies between different centers. The aim of this study was to investigate the role of perioperative antibiotic prophylaxis in preventing postoperative complications. Methods 700 patients who underwent cochlear implantation between 2007 and 2019 were retrospectively evaluated with regard to wound infections within the first 28 postoperative days. These were classified into major and minor complications. Data were analyzed using the IBM statistical program SPSS. Results In 670 out of 700 patients the type and duration of perioperative antibiotic administration could be reconstructed from the records. Of these 67 patients (10%) received antibiotics as a single shot, 158 patients (23.6%) were treated with antibiotics for a period of 48 h, and 445 patients (66.4%) received prolonged antibiotic therapy for more than 72 h. In total 64 patients (9.5%) showed abnormalities in wound assessment within the first 28 postoperative days after implantation. Major infections (1.6%) were detected in 11 patients. Overall, there was no statistically significant difference in wound infection rates between the group receiving single-shot antibiosis and the group receiving 48 h prophylaxis or antibiotic treatment > 72 h (p = 0.46). Conclusion Patients receiving an antibiotic single shot do not appear to be at significantly increased risk for postoperative wound infections compared with patients with prolonged antibiotic treatment. Continuation of data collection across centers seems reasonable.
Druh dokumentu: Article
Other literature type
Popis souboru: Text
Jazyk: English
ISSN: 1434-4726
0937-4477
DOI: 10.1007/s00405-024-08515-1
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38480534
https://repository.publisso.de/resource/frl:6519093
Rights: CC BY
Přístupové číslo: edsair.doi.dedup.....fdd8eaba08d37dac4871329f5062e7f3
Databáze: OpenAIRE
Popis
Abstrakt:Purpose Postoperative wound infections after cochlear implantation are rare but sometimes serious and can lead to explantation. Therefore, perioperative antibiotic administration is often recommended. However, in clinical practice, the type and duration of antibiotic prophylaxis varies between different centers. The aim of this study was to investigate the role of perioperative antibiotic prophylaxis in preventing postoperative complications. Methods 700 patients who underwent cochlear implantation between 2007 and 2019 were retrospectively evaluated with regard to wound infections within the first 28 postoperative days. These were classified into major and minor complications. Data were analyzed using the IBM statistical program SPSS. Results In 670 out of 700 patients the type and duration of perioperative antibiotic administration could be reconstructed from the records. Of these 67 patients (10%) received antibiotics as a single shot, 158 patients (23.6%) were treated with antibiotics for a period of 48 h, and 445 patients (66.4%) received prolonged antibiotic therapy for more than 72 h. In total 64 patients (9.5%) showed abnormalities in wound assessment within the first 28 postoperative days after implantation. Major infections (1.6%) were detected in 11 patients. Overall, there was no statistically significant difference in wound infection rates between the group receiving single-shot antibiosis and the group receiving 48 h prophylaxis or antibiotic treatment > 72 h (p = 0.46). Conclusion Patients receiving an antibiotic single shot do not appear to be at significantly increased risk for postoperative wound infections compared with patients with prolonged antibiotic treatment. Continuation of data collection across centers seems reasonable.
ISSN:14344726
09374477
DOI:10.1007/s00405-024-08515-1