European Society of Anaesthesiology Task Force on Nitrous Oxide: a narrative review of its role in clinical practice
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| Název: | European Society of Anaesthesiology Task Force on Nitrous Oxide: a narrative review of its role in clinical practice |
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| Autoři: | Buhre, Wolfgang, Disma, Nicola, Hendrickx, Jan, DeHert, Stefan, Hollmann, Markus W, Huhn, Ragnar, Jakobsson, Jan, Nagele, Peter, Peyton, Philip, Vutskits, Laszlo |
| Zdroj: | British Journal of Anaesthesia. 122:587-604 |
| Informace o vydavateli: | Elsevier BV, 2019. |
| Rok vydání: | 2019 |
| Témata: | Anesthesia, Dental, Evidence-Based Medicine/methods, Conscious Sedation, Nitrous Oxide, Antidepressive Agents/therapeutic use, 03 medical and health sciences, 0302 clinical medicine, Non-Narcotic/adverse effects/pharmacology/therapeutic use, Humans, Anesthesia, Dental/methods, Anesthetics, Conscious Sedation/methods, Nitrous Oxide/adverse effects/pharmacology/therapeutic use, Analgesics, Depressive Disorder, Depressive Disorder, Major, Evidence-Based Medicine, Contraindications, Obstetrical/methods, Contraindications, Drug, Inhalation/adverse effects/pharmacology, Chronic Pain/prevention & control, Analgesics, Non-Narcotic, Antidepressive Agents, 3. Good health, Major/drug therapy, Anesthetics, Inhalation, Analgesia, Obstetrical, Analgesia, Drug, Chronic Pain |
| Popis: | Nitrous oxide (N2O) is one of the oldest drugs still in use in medicine. Despite its superior pharmacokinetic properties, controversy remains over its continued use in clinical practice, reflecting in part significant improvements in the pharmacology of other anaesthetic agents and developing awareness of its shortcomings. This narrative review describes current knowledge regarding the clinical use of N2O based on a systematic and critical analysis of the available scientific literature. The pharmacological properties of N2O are reviewed in detail along with current evidence for the indications and contraindications of this drug in specific settings, both in perioperative care and in procedural sedation. Novel potential applications for N2O for the prevention or treatment of chronic pain and depression are also discussed. In view of the available evidence, we recommend that the supply of N2O in hospitals be maintained while encouraging its economic delivery using modern low flow delivery systems. Future research into its potential novel applications in prevention or treatment of chronic conditions should be pursued to better identify its role place in the developing era of precision medicine. |
| Druh dokumentu: | Article |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 0007-0912 |
| DOI: | 10.1016/j.bja.2019.01.023 |
| Přístupová URL adresa: | http://bjanaesthesia.org/article/S0007091219300637/pdf https://pubmed.ncbi.nlm.nih.gov/30916011 https://www.bjanaesthesia.org.uk/article/S0007-0912(19)30063-7/fulltext https://www.sciencedirect.com/science/article/abs/pii/S0007091219300637 https://www.bjanaesthesia.org/article/S0007-0912(19)30063-7/fulltext https://ahro.austin.org.au/austinjspui/handle/1/20503?mode=full https://moh-it.pure.elsevier.com/en/publications/european-society-of-anaesthesiology-task-force-on-nitrous-oxide-a https://www.narcis.nl/publication/RecordID/oai%3Apure.amc.nl%3Apublications%2Fbe5041c2-8680-4c0f-ba5f-b1a753b91b7e |
| Rights: | Elsevier Non-Commercial |
| Přístupové číslo: | edsair.doi.dedup.....fa796b3b4085e5d402b8edbdc76c3223 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Nitrous oxide (N2O) is one of the oldest drugs still in use in medicine. Despite its superior pharmacokinetic properties, controversy remains over its continued use in clinical practice, reflecting in part significant improvements in the pharmacology of other anaesthetic agents and developing awareness of its shortcomings. This narrative review describes current knowledge regarding the clinical use of N2O based on a systematic and critical analysis of the available scientific literature. The pharmacological properties of N2O are reviewed in detail along with current evidence for the indications and contraindications of this drug in specific settings, both in perioperative care and in procedural sedation. Novel potential applications for N2O for the prevention or treatment of chronic pain and depression are also discussed. In view of the available evidence, we recommend that the supply of N2O in hospitals be maintained while encouraging its economic delivery using modern low flow delivery systems. Future research into its potential novel applications in prevention or treatment of chronic conditions should be pursued to better identify its role place in the developing era of precision medicine. |
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| ISSN: | 00070912 |
| DOI: | 10.1016/j.bja.2019.01.023 |