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Surfactant-free electrochemical synthesis of fluoridated hydroxyapatite nanorods for biomedical applications

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Názov: Surfactant-free electrochemical synthesis of fluoridated hydroxyapatite nanorods for biomedical applications
Autori: Xinxin An, Menghao Wang, Kefeng Wang, Guang Chen, Zhaoyang Li, Xiong Lu, Bao Qian, Qun Wang, Chengzu Ren, Fuzeng Ren, Xiang Ge
Zdroj: Ceramics International. 45:17336-17343
Informácie o vydavateľovi: Elsevier BV, 2019.
Rok vydania: 2019
Predmety: Electrochemical, Nanorods, Fluoridated hydroxyapatite (FHA), 02 engineering and technology, Surfactant-free, Transmission electron microscopy (TEM), 0210 nano-technology, High resolution TEM (HRTEM), 01 natural sciences, 3. Good health, 0104 chemical sciences
Popis: Fluoridated hydroxyapatite (FHA) [Ca10(PO4)6Fx(OH)2−x, x = 0–2] is believed to be a promising calcium phosphate (CaP) to replace pure hydroxyapatite (HA) for next-generation implants, owing to its better biocompatibility, higher antibacterial activity, and lower solubility. Notably, the shape and size of the CaP crystals play key roles in their performance and can influence their applications. One-dimensional (1D) FHA nanorods are important CaP materials which have been widely used in regenerative medicine applications such as restorative dentistry. Unfortunately, the traditional synthesis methods for FHA nanorods either employ surfactants or take a relatively long time. In this study, we aimed to propose a facile synthesis route to fabricate FHA nanorods without any surfactants using an electrochemical deposition method for the first time. This study focused on preparing FHA nanorods without the assistance of any surfactant, unlike the traditional synthesis methods, to avoid chemical impurities. FHA nanorods with lengths of 124–2606 nm, diameters of 28–211 nm, and aspect ratios of 4.4–21.8 were synthesized using the electrochemical method, followed by a heat treatment. For the as-synthesized FHA nanorods, the Ca/P ratio was 1.60 and the atomic concentration of F was 2.06 at.%. An ultrastructure examination revealed that each FHA nanorod possessed long-range order, good crystallinity, and a defect-free lattice with a certain crystallographic plane orientation along the whole rod. In short, we propose a novel, surfactant-free, cost-saving, and more efficient route to synthesize FHA nanorods which can be widely applied in multiple biomedical applications, including drug delivery, bone repair, and restorative dentistry.
Druh dokumentu: Article
Jazyk: English
ISSN: 0272-8842
DOI: 10.1016/j.ceramint.2019.05.292
Prístupová URL adresa: https://www.sciencedirect.com/science/article/pii/S0272884219314051
Rights: Elsevier TDM
Prístupové číslo: edsair.doi.dedup.....f841058cc5c08e01df26b3fa62209079
Databáza: OpenAIRE
Popis
Abstrakt:Fluoridated hydroxyapatite (FHA) [Ca10(PO4)6Fx(OH)2−x, x = 0–2] is believed to be a promising calcium phosphate (CaP) to replace pure hydroxyapatite (HA) for next-generation implants, owing to its better biocompatibility, higher antibacterial activity, and lower solubility. Notably, the shape and size of the CaP crystals play key roles in their performance and can influence their applications. One-dimensional (1D) FHA nanorods are important CaP materials which have been widely used in regenerative medicine applications such as restorative dentistry. Unfortunately, the traditional synthesis methods for FHA nanorods either employ surfactants or take a relatively long time. In this study, we aimed to propose a facile synthesis route to fabricate FHA nanorods without any surfactants using an electrochemical deposition method for the first time. This study focused on preparing FHA nanorods without the assistance of any surfactant, unlike the traditional synthesis methods, to avoid chemical impurities. FHA nanorods with lengths of 124–2606 nm, diameters of 28–211 nm, and aspect ratios of 4.4–21.8 were synthesized using the electrochemical method, followed by a heat treatment. For the as-synthesized FHA nanorods, the Ca/P ratio was 1.60 and the atomic concentration of F was 2.06 at.%. An ultrastructure examination revealed that each FHA nanorod possessed long-range order, good crystallinity, and a defect-free lattice with a certain crystallographic plane orientation along the whole rod. In short, we propose a novel, surfactant-free, cost-saving, and more efficient route to synthesize FHA nanorods which can be widely applied in multiple biomedical applications, including drug delivery, bone repair, and restorative dentistry.
ISSN:02728842
DOI:10.1016/j.ceramint.2019.05.292