Adjunctive benzodiazepine treatment of hospitalized schizophrenia patients in Asia from 2001 to 2008
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| Názov: | Adjunctive benzodiazepine treatment of hospitalized schizophrenia patients in Asia from 2001 to 2008 |
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| Autori: | Ross J. Baldessarini, Edwin Ho Ming Lee, Mian-Yoon Chong, Eun Kee Chung, Kang Sim, Norman Sartorius, Chay Hoon Tan, Senta Fujii, Phern-Chern Tor, Naotaka Shinfuku, Yanling He, Yu-Tao Xiang, Chuanyue Wang, Shu Yu Yang, Pichet Udomratn, J K Trivedi, Gabor S. Ungvari, Kok Yoon Chee, Tian-Mei Si, Kian-Hui Yong, Tze Pin Ng, Ee Heok Kua |
| Prispievatelia: | PSYCHOLOGICAL MEDICINE |
| Zdroj: | The International Journal of Neuropsychopharmacology. 14:735-745 |
| Informácie o vydavateľovi: | Oxford University Press (OUP), 2011. |
| Rok vydania: | 2011 |
| Predmety: | Adult, Male, Asia, Statistics as Topic, Physician's Practice Patterns, Diagnostic And Statistical Manual Of Mental Disorders, Benzodiazepines, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Drug Therapy, Humans, Drug Therapy, Combination - Adverse Effects, Statistics As Topic, Practice Patterns, Physicians', Psychotropic Drugs - Administration & Dosage - Adverse Effects - Therapeutic Use, Aged, Psychotropic Drugs, Benzodiazepines - Administration & Dosage - Adverse Effects - Therapeutic Use, Combination - Adverse Effects, Middle Aged, Practice Guidelines As Topic, 3. Good health, Diagnostic and Statistical Manual of Mental Disorders, Hospitalization, Cross-Sectional Studies, Practice Guidelines as Topic, Schizophrenia, Drug Therapy, Combination, Female, Schizophrenia - Drug Therapy - Physiopathology |
| Popis: | Benzodiazepines are commonly prescribed to patients with schizophrenia in many countries, but as little is known about such treatment in Asia, we evaluated their adjunctive use for 6761 in-patients diagnosed with schizophrenia in nine Asian countries using a cross-sectional study design in 2001, 2004 and 2008. Multivariate logistic regression and multivariate linear regression analyses were performed to assess predictors of benzodiazepine use and dose, respectively. Overall, 54% of the patients received adjunctive benzodiazepines at an average daily dose equivalent to 30.3 mg diazepam, with minor changes over the years sampled. Benzodiazepine use was highest in Taiwan and Japan, lowest in Thailand and China, and was associated with fewer years ill, presence of delusions (OR 1.24), hallucinations (OR 1.22), disorganized speech (OR 1.17), social or occupational dysfunction (OR 1.16), and use of mood stabilizers (OR 3.15), antiparkinsonian (OR 1.79) or antidepressant drugs (OR 1.33), and lower doses of antipsychotics (all p=0.016 to |
| Druh dokumentu: | Article |
| Jazyk: | English |
| ISSN: | 1469-5111 1461-1457 |
| DOI: | 10.1017/s146114571000163x |
| Prístupová URL adresa: | https://academic.oup.com/ijnp/article-pdf/14/6/735/2713448/14-6-735.pdf https://pubmed.ncbi.nlm.nih.gov/21294941 https://europepmc.org/article/MED/21294941 https://academic.oup.com/ijnp/article/14/6/735/916161 https://hub.hku.hk/handle/10722/171963 http://hub.hku.hk/bitstream/10722/171963/1/Content.pdf https://pubmed.ncbi.nlm.nih.gov/21294941/ https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201302297590930854 http://hdl.handle.net/10722/171963 |
| Rights: | implied-oa CC BY NC ND |
| Prístupové číslo: | edsair.doi.dedup.....f7a37fcc71923ec8cb2c5fa992172af2 |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Benzodiazepines are commonly prescribed to patients with schizophrenia in many countries, but as little is known about such treatment in Asia, we evaluated their adjunctive use for 6761 in-patients diagnosed with schizophrenia in nine Asian countries using a cross-sectional study design in 2001, 2004 and 2008. Multivariate logistic regression and multivariate linear regression analyses were performed to assess predictors of benzodiazepine use and dose, respectively. Overall, 54% of the patients received adjunctive benzodiazepines at an average daily dose equivalent to 30.3 mg diazepam, with minor changes over the years sampled. Benzodiazepine use was highest in Taiwan and Japan, lowest in Thailand and China, and was associated with fewer years ill, presence of delusions (OR 1.24), hallucinations (OR 1.22), disorganized speech (OR 1.17), social or occupational dysfunction (OR 1.16), and use of mood stabilizers (OR 3.15), antiparkinsonian (OR 1.79) or antidepressant drugs (OR 1.33), and lower doses of antipsychotics (all p=0.016 to |
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| ISSN: | 14695111 14611457 |
| DOI: | 10.1017/s146114571000163x |