Narrative review of diagnosis, management and treatment of dysphagia and sialorrhea in amyotrophic lateral sclerosis

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Název: Narrative review of diagnosis, management and treatment of dysphagia and sialorrhea in amyotrophic lateral sclerosis
Autoři: Bogdan Bjelica, Susanne Petri
Zdroj: J Neurol
Informace o vydavateli: Springer Science and Business Media LLC, 2024.
Rok vydání: 2024
Témata: Amyotrophic lateral sclerosis, Sialorrhea/therapy [MeSH], Humans [MeSH], Sialorrhea, Dysphagia, Disease Management [MeSH], Amyotrophic Lateral Sclerosis/diagnosis [MeSH], Amyotrophic Lateral Sclerosis/complications [MeSH], Motor neuron disease, Deglutition Disorders/physiopathology [MeSH], Sialorrhea/diagnosis [MeSH], Sialorrhea/etiology [MeSH], ALS, Deglutition Disorders/therapy [MeSH], Review, Deglutition Disorders/diagnosis [MeSH], Amyotrophic Lateral Sclerosis/therapy [MeSH], Deglutition Disorders/etiology [MeSH], 03 medical and health sciences, 0302 clinical medicine, Amyotrophic Lateral Sclerosis, Humans, Disease Management, Deglutition Disorders
Popis: The degenerative motor neuron disorder amyotrophic lateral sclerosis (ALS) frequently leads bulbar symptoms like dysarthria, dysphagia, and sialorrhea, in approximately one-third of cases being the initial symptom. Throughout the disease, more than two-thirds of ALS patients experience dysphagia, regardless of the region of onset. In this review, we aimed to offer an updated overview of dysphagia and sialorrhea in ALS, covering its diagnosis, monitoring, and treatment in clinical practice. Regular assessment of dysphagia and sialorrhea during each patient visit is essential and should be a standard aspect of ALS care. Early discussion of potential treatments such as high-calorie diets or percutaneous endoscopic gastrostomy (PEG) is crucial. Furthermore, this review highlights and discusses potential areas for improvement in both clinical practice and research.
Druh dokumentu: Article
Other literature type
Jazyk: English
ISSN: 1432-1459
0340-5354
DOI: 10.1007/s00415-024-12657-x
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39207520
https://repository.publisso.de/resource/frl:6497588
Rights: CC BY
Přístupové číslo: edsair.doi.dedup.....f7610278ab6f9a05dc217f72db1675f1
Databáze: OpenAIRE
Popis
Abstrakt:The degenerative motor neuron disorder amyotrophic lateral sclerosis (ALS) frequently leads bulbar symptoms like dysarthria, dysphagia, and sialorrhea, in approximately one-third of cases being the initial symptom. Throughout the disease, more than two-thirds of ALS patients experience dysphagia, regardless of the region of onset. In this review, we aimed to offer an updated overview of dysphagia and sialorrhea in ALS, covering its diagnosis, monitoring, and treatment in clinical practice. Regular assessment of dysphagia and sialorrhea during each patient visit is essential and should be a standard aspect of ALS care. Early discussion of potential treatments such as high-calorie diets or percutaneous endoscopic gastrostomy (PEG) is crucial. Furthermore, this review highlights and discusses potential areas for improvement in both clinical practice and research.
ISSN:14321459
03405354
DOI:10.1007/s00415-024-12657-x