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The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations: evaluation of the ERC-ESICM recommendations

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Názov:	The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations: evaluation of the ERC-ESICM recommendations
Autori:	Turella, Sara, Dankiewicz, Josef, Friberg, Hans, Jakobsen, Janus Christian, Leithner, Christoph, Levin, Helena, Lilja, Gisela, Moseby-Knappe, Marion, Nielsen, Niklas, Rossetti, Andrea O., Sandroni, Claudio, Zubler, Frédéric, Cronberg, Tobias, Westhall, Erik, the TTM2-trial investigators, Bělohlávek, Jan, Callaway, Clifton, Cariou, Alain, Eastwood, Glenn, Erlinge, David, Hovdenes, Jan, Joannidis, Michael, Kirkegaard, Hans, Morgan, Matt P. G, Nichol, Alistair D, Nordberg, Per, Oddo, Mauro, Pelosi, Paolo, Rylander, Christian, Saxena, Manoj, Storm, Christian, Taccone, Fabio S, Ullén, Susann, Wise, Matt P, Young, Paul J, Rowan, Kathy, Mouncey, Paul, Shankar-Hari, Manu, Young, Duncan, Lange, Theis, Palmér, Karolina, Karlsson, Ulla-Britt, Heissler, Simon, Bass, Frances, Hammond, Naomi, Myburgh, John, Taylor, Colman, Bellino, Adele, Abel-all, Marwa, Finfer, Ben, Koch, Carolyn, Li, Yang, O’Connor, Anne, Pilowsky, Julia, Schneider, Tina, Tippett, Anna, Ady, Bridget, Broadley, Tessa, Brown, Amanda, Melgaard, Liz, Morgan, Mimi, Singh, Vanessa, Symons, Rebecca, Becker, Kathrin, Van Sante, Nathalie, Saleova, Vendula, Zerzanova, Silvie, Sefr-Kribel, Samia, Lübeck, Ute, Carrara, Martina, Fernando, Kathryn, Mackle, Diane, Navarra, Leanlove, Riley, Judith, Westerheim, Elin, Flatebø, Marianne, Ceric, Ameldina, Haxhija, Zana, Terling, Lovisa, Bossmar, Lena, Jergle, Liz, Månsson, Helén Holm, Maillard, Samia Abed, Zagar, Andreja Vujicic, Jodlauk, Christina, Hill, Helen, Scrivens, Jennifer, Ainscough, Kate, Fahey, Ciara, Bellomo, Rinaldo, Peck, Leah, Young, Helen, Cheung, Winston, Cross, Rosalba, Hayes, Michael, Jain, Nitin, Kol, Mark, Shah, Asim, Wagh, Atul, Wong, Helen, Martinez, F. Eduardo, Brinkerhof, Gail, Bush, Dustin, Stewart, Antony, Aneman, Anders, Lombardo, Lien, McCanny, Peter, Penketh, James, Seppelt, Ian, Gresham, Rebecca, Lowrey, Julie, Masters, Kristy, Whitehead, Christina, Walsham, James, Harward, Meg, Mackay, Josephine, Meyer, Jason, Saylor, Emma, Venz, Ellen, Wetzig, Krista, Stedman, Wade, Ashelford, Angela, Mar, Sharon, Tokumitsu, Miyuki, Yarad, Elizabeth, Buscher, Hergen, Reynolds, Claire, Udy, Andrew, Burrell, Aidan, Collins, Jasmin, Gantner, Dashiell, Martin, Victoria Emma-Leah, Mccracken, Phoebe, Nanjayya, Vinodh, Nichol, Alistair, Richardson, Alexander Sacha, Young, Meredith, Ghosh, Angaj, Said, Simone, Beer, Ronny, Hartig, Frank, Helbok, Raimund, Klein, Sebastian, Peer, Andreas, Creteur, Jacques, Durand, Dominique, Dupont, Matthias, Christiaens, Sigrid, Claes, Carola, Deckx, Sebastiaan, Ferdinande, Bert, Lenaerts, Sanne, Mullens, Wilifred, Stroobants, Sarah, Theunissen, Evi, Verhaert, David, Šmíd, Ondřej, Flaksa, Marek, Kemlink, David, Malík, Jan, Otáhal, Michal, Rulíšek, Jan, Šíranec, Michal, Stach, Zdeněk, Valeriánová, Anna, Zavadilova, Petra, Solař, Miroslav, Bánszky, Róber, Červená, Jana, Pařízková, Renata Černá, Šimůnek, Libor, Varhaník, Filip, Karásek, Jiří, Strýček, Matěj, Grejs, Anders, Christensen, Stefen, Juhl-Olsen, Peter, Thomsen, Ida Katrine, Østergaard, Lisa Gregersen, Cao, Albert, Dupland, Pierre, Gavaud, Ariane, Jaubert, Paul, Jozwiak, Mathieu, Marin, Nathalie, Savary, Guillaume, Deye, Nicolas, Megarbane, Bruno, Mora, Pierre, Sutterlin, Laetitia, Legriel, Stephane, Bellut, Hugo, Ferre, Alexis, Lacave, Guillaume, Paul, Marine, Lascarrou, Jean-Baptiste, Canet, Emmanuel, Garret, Charlotte, Miaihle, Arnaud Felix, Reignier, Jean, Vignon, Philippe, Daix, Thomas, Desachy, Arnaud, Evrard, Bruno, Francois, Bruno, Fedou, Anne-Laure, Goudelin, Marine, Kress, Gabriele, Nee, Jens, Streitberger, Kaspar Josche, Brunetti, Iole, Ball, Lorenzo, Battaglini, Denise, Bonatti, Giulia, Firpo, Iacopo, Frisoni, Paolo, Iachi, Arianna, Maiani, Simona, Mandelli, Maura, Robba, Chiara, Tarantino, Fabio, Barbieri, Alberto, Bertellini, Elisabetta, Giuliani, Enrico, Melegari, Gabriele, Roman-Pognuz, Erik, Berlot, Giorgio, Lucangelo, Umberto, Macchini, Elisabetta, Aune, Vibeke, Drægni, Tomas, Jacobsen, Simon, Pieschke, Søren, Rasmussen, Åse, Akselsen, Gro Ringstad, Langeland, Halvor, Bergum, Daniel, Erbe, Therese M., Klepstad, Pål, Næss, Helle M, Olsen, Roy Bjørkholt, Skjelnes, Lena Eriksen, Holen, Marius, Post, Joakim Iver, Fanebust, Rune, Sørensen, Linda Hårteig, Kårstad, Ken Åge, Wickman, Carsten Fredrik, Young, Paul, Barnes, Colin, Barry, Ben, Beehre, Nina, Dinsdale, Dick, Edney, Sam, Hunt, Anna, Judd, Harriet, Latimer-Bell, Charlotte, Lawrence, Cassie, Moore, James, Olatunji, Shaanti, Psirides, Alex, Robinson, Chelsea, Tietjens, Kate, Wright, Jason, Knight, David, Birker, Brandon, Bowie, David, Burke, Tara, Closey, David, Crombie, Rosalind, Davidson, Neil, Henderson, Seton, Hitchings, Louise, McKay, James, Mehrtens, Jan, Minto, Emmeline, Morgan, Stacey, Morris, Anna, Ritzemar-Carter, Jay, Roberts, Jessica, Shaw, Geofrey, Townend, Katherine, Heyden, Kymbalee Vander, Ahlqvist, Marita, Lindgren, Roman Desta, Eiving, Ingrid, Lundin, Andreas, Martner, Patrik, Myhrman, Elisabeth, Ryding, Birgitta, Düring, Joachim, Bergström, Mattias, Bohm, Mattias, Didriksson, Ingrid, Frid, Petrea, Heimburg, Katarina, Larsson, Marina, Lundberg, Oscar, Hau, Stefan Olsson, Schmidbauer, Simon, Borgquist, Ola, Adolfsson, Anne, Bjärnroos, Anna, Blennow-Nordström, Erik, Dragancea, Irina, Kander, Thomas, Lybeck, Anna, Mattiasson, Gustav, Persson, Olof, Rundgren, Malin, Schrey, Susann, Annborn, Martin, Andertun, Sara, Ebner, Florian, Gustavsson, Nerida, Hassel, Lisa, Johnsson, Jesper, Nelderup, Marie, Petersson, Heléne, Petersson, Jörgen, Staflidou, Frideriki, Undén, Johan, Antonsson, Frida, Bergman, Git, Gamroth, Jörgen, Meirik, Maria, Rudolfsson, Katarina, Sandberg, Helena, Thorsson, Martin, Savolainen, Kristin, Hansbo, Maria, Helliksson, Malin, Nödtveidt, Björne, Sanner, Johan, Sem, Victoria, Lindquist, Camilla Sund, Awad, Akil, Börjesson, Anna-Sofa, Hedberg, Malin, Henning, Mia, Hollenberg, Jacob, Petersen, Per, Dahlberg, Emelia, Forshammar, Johan, Svensson, Veronica, Wanecek, Michael, Eskilsson, Håkan, Rodriguez-Santos, Daniel, Appelqvist, Åsa, Jidbratt, Henrietta, Johansson, Elisabeth, Kiszakiewicz, Lars, Nilsson, Åsa, Olsson, Sinnika, Paulsson, Anders, Stempel, Urszula, Thoren, Andreas, Persson, Stefan, Berglund, Ida, Bergström, Eric, Törnqvist, Cathrine, Östman, Ingela, Rubertsson, Sten, Larsson, Ing-Marie, Söderman, Elin, Wallin, Ewa, Wessbergh, Joanna, Halliday, Thomas, Engvall, Filippa, Ben-Hamouda, Nawfel, Bernini, Adriano, Carron, Pierre-Nicolas, Eckert, Philippe, Favre, Eva, Miroz, John-Paul, Morelli, Paola, Muller, Olivier, Novi, Jan, Rosseti, Andrea, Schnorf, Madeleine, Haenggi, Matthias, Levis, Anja, Nansoz, Sandra, Roth, Marianne, Söll, Nicole, Schrag, Claudia, Alicajic, Mensur, Baier, Philipp, Dütschler, Joel, Flügel, Dominique, Fässler, Edith, Gamio-Veis, Ruth, Güpfert, Marc, Hilpertshauser, Yvonne, Hägele-Link, Stefan, Kleger, Gian-Reto, Krähenmann, Peter, Mair, Maria Elisabeth, Schai, Nadja, Strohmaier, Christoph, Tangl, Peter, Zieglgänsberger, Dominik, Maggiorini, Marco, Claus, Gabriele, Vogel, Gabi Consani, Imbach, Lukas, Kaiser, Samira, Kleinert, Eva-Maria, Garcia, Pedro David Wendel, Cassina, Tiziano, Agazzi, Pamela, Capelli, Bruno, Casso, Gabriele, Regazzi, Martino, Schlotterbeck, Hervé, Via, Gabriele, Villa, Michele, Brooks, Jenny, Cocks, Eve, Cole, Jade, Curtin, Jacqueline, Davies, Michelle, Davies, Rhys, Fernandez, Stephen, Highfeld, Julie, Pennant, Lydia, Rose, Sofa, Thomas, Emma, Williams, Angharad, McGuigan, Peter, Hafey, Stephen, O’Neill, Aisling, Ward, Kathryn, Thomas, Matthew, Bewley, Jeremy, Chillingworth, Anna, Cloake, Julie, Cole, Libby, Galvin, Hilary, Garland, Zoe, Grimmer, Lisa, Gumbrill, Bethany, Howie, Lucy, Johnson, Rebekah, Searles, Chloe, Skorko, Agnieszka, Sweet, Katie, Taylor, Victoria, Webster, Denise, Keeble, Thomas, Adams, Gill, Aggarwal, Rajesh K, Cartwright, Jo-Anne, Church, Steven, Clesham, Gerald J, Davies, John R, Farrell, Kelly, Gamma, Reto, Harding, Jane, Jagathesan, Rohan, Kabir, Alamgir, Kelly, Paul A, Kittridge, Lauren, Maccaroni, Maria, Maloney, Gracie, Mion, Marco, Nain, Naveen, Nalgirkar, Raghunath, Namjoshi, Gyanesh, Pepper, Stacey, Redman, Emily, Robinson, Nicholas M, Sayer, Jeremy, Solesbury, Amanda, Tang, Kare H, Urovi, Sali, Waghmare, Kunal, Watson, Noel, Webber, Teresa, Isherwood, Peter, Bentley, Conor, Bergin, Colin, Carrera, Ronald, Clark, Amy, Cooper, Lauren, Despy, Liesl, Dooley, Natalie, Ellis, Karen, Fellows, Emma, Goundry, Stephanie, Harkett, Samantha, McGhee, Christopher, Neal, Aoife, Smith, Hazel, Snelson, Catherine, Spruce, Elaine, Whitehouse, Tony, Yakoub, Kamal, Walden, Andrew, Bartley, Shauna, Bhuie, Parminder, Frise, Matthew, Jacques, Nicola, Keating, Liza, Pogson, David, Daly, Zoe, Rose, Steve, Bannard-Smith, Jonathan, Quayle, Rachael, Chee, Nigel, Barratt, Nina, Bowman, Katie, Branney, Debbie, Howe, Elizabeth, Letts, Maria, Pitts, Sally, Vamplew, Luke, Callaway, Clifton W, Sprouse, Sara Difore, Doshi, Ankur A, Fugate, Jennifer, Headlee, Amy M, Wijdicks, Eelco F.M.
Prispievatelia:	Turella, Sara, Dankiewicz, Josef, Friberg, Han, Christian Jakobsen, Janu, Leithner, Christoph, Levin, Helena, Lilja, Gisela, Moseby-Knappe, Marion, Nielsen, Nikla, Rossetti, Andrea O., Sandroni, Claudio, Zubler, Frédéric, Cronberg, Tobia, Westhall, Erik, Bělohlávek, Jan, Callaway, Clifton, Cariou, Alain, Eastwood, Glenn, Erlinge, David, Hovdenes, Jan, Joannidis, Michael, Kirkegaard, Han, G Morgan, Matt P., D Nichol, Alistair, Nordberg, Per, Oddo, Mauro, Pelosi, Paolo, Rylander, Christian, Saxena, Manoj, Storm, Christian, S Taccone, Fabio, Ullén, Susann, P Wise, Matt, J Young, Paul, Rowan, Kathy, Mouncey, Paul, Shankar-Hari, Manu, Young, Duncan, Lange, Thei, Palmér, Karolina, Karlsson, Ulla-Britt, Heissler, Simon, Bass, France, Hammond, Naomi, Myburgh, John, Taylor, Colman, Roman-Pognuz, Erik, Investigators, TTM2-trial, TTM2-trial investigators, Bělohlávek, J., Callaway, C., Cariou, A., Cronberg, T., Eastwood, G., Erlinge, D., Hovdenes, J., Joannidis, M., Kirkegaard, H., Morgan, MPG, Nichol, A.D., Nordberg, P., Oddo, M., Pelosi, P., Rylander, C., Saxena, M., Storm, C., Taccone, F.S., Ullén, S., Wise, M.P., Young, P.J., Rowan, K., Mouncey, P., Shankar-Hari, M., Young, D., Lange, T., Palmér, K., Karlsson, U.B., Heissler, S., Bass, F., Hammond, N., Myburgh, J., Taylor, C., Bellino, A., Abel-All, M., Finfer, B., Koch, C., Li, Y., O'Connor, A., Pilowsky, J., Schneider, T., Tippett, A., Ady, B., Broadley, T., Brown, A., Melgaard, L., Morgan, M., Singh, V., Symons, R., Becker, K., Van Sante, N., Saleova, V., Zerzanova, S., Sefr-Kribel, S., Lübeck, U., Carrara, M., Fernando, K., Mackle, D., Navarra, L., Riley, J., Westerheim, E., Flatebø, M., Ceric, A., Haxhija, Z., Terling, L., Bossmar, L., Jergle, L., Månsson, H.H., Maillard, S.A., Zagar, A.V., Jodlauk, C., Hill, H., Scrivens, J., Ainscough, K., Fahey, C., Bellomo, R., Peck, L., Young, H., Cheung, W., Cross, R., Hayes, M., Jain, N., Kol, M., Shah, A., Wagh, A., Wong, H., Martinez, F.E., Brinkerhof, G., Bush, D., Stewart, A., Aneman, A., Lombardo, L., McCanny, P., Penketh, J., Seppelt, I., Gresham, R., Lowrey, J., Masters, K., Whitehead, C., Walsham, J., Harward, M., Mackay, J., Meyer, J., Saylor, E., Venz, E., Wetzig, K., Stedman, W., Ashelford, A., Mar, S., Tokumitsu, M., Yarad, E., Buscher, H., Reynolds, C., Udy, A., Burrell, A., Collins, J., Gantner, D., Martin, V.E., Mccracken, P., Nanjayya, V., Nichol, A., Richardson, A.S., Young, M., Ghosh, A., Said, S., Beer, R., Hartig, F., Helbok, R., Klein, S., Peer, A., Creteur, J., Durand, D., Dupont, M., Christiaens, S., Claes, C., Deckx, S., Ferdinande, B., Lenaerts, S., Mullens, W., Stroobants, S., Theunissen, E., Verhaert, D., Šmíd, O., Flaksa, M., Kemlink, D., Malík, J., Otáhal, M., Rulíšek, J., Šíranec, M., Stach, Z., Valeriánová, A., Zavadilova, P., Solař, M., Bánszky, R., Červená, J., Pařízková, R.Č., Šimůnek, L., Varhaník, F., Karásek, J., Strýček, M., Grejs, A., Christensen, S., Juhl-Olsen, P., Thomsen, I.K., Østergaard, L.G., Cao, A., Dupland, P., Gavaud, A., Jaubert, P., Jozwiak, M., Marin, N., Savary, G., Deye, N., Megarbane, B., Mora, P., Sutterlin, L., Legriel, S., Bellut, H., Ferre, A., Lacave, G., Paul, M., Lascarrou, J.B., Canet, E., Garret, C., Miaihle, A.F., Reignier, J., Vignon, P., Daix, T., Desachy, A., Evrard, B., Francois, B., Fedou, A.L., Goudelin, M., Kress, G., Nee, J., Streitberger, K.J., Brunetti, I., Ball, L., Battaglini, D., Bonatti, G., Firpo, I., Frisoni, P., Iachi, A., Maiani, S., Mandelli, M., Robba, C., Tarantino, F., Barbieri, A., Bertellini, E., Giuliani, E., Melegari, G., Roman-Pognuz, E., Berlot, G., Lucangelo, U., Macchini, E., Aune, V., Drægni, T., Jacobsen, S., Pieschke, S., Rasmussen, Å., Akselsen, G.R., Langeland, H., Bergum, D., Erbe, T.M., Klepstad, P., Næss, H.M., Olsen, R.B., Skjelnes, L.E., Holen, M., Post, J.I., Fanebust, R., Sørensen, L.H., Kårstad, K.Å., Wickman, C.F., Young, P., Barnes, C., Barry, B., Beehre, N., Dinsdale, D., Edney, S., Hunt, A., Judd, H., Latimer-Bell, C., Lawrence, C., Moore, J., Olatunji, S., Psirides, A., Robinson, C., Tietjens, K., Wright, J., Knight, D., Birker, B., Bowie, D., Burke, T., Closey, D., Crombie, R., Davidson, N., Henderson, S., Hitchings, L., McKay, J., Mehrtens, J., Minto, E., Morgan, S., Morris, A., Ritzemar-Carter, J., Roberts, J., Shaw, G., Townend, K., Heyden, K.V., Ahlqvist, M., Lindgren, R.D., Eiving, I., Lundin, A., Martner, P., Myhrman, E., Ryding, B., Düring, J., Bergström, M., Bohm, M., Didriksson, I., Frid, P., Heimburg, K., Larsson, M., Lundberg, O., Hau, S.O., Schmidbauer, S., Borgquist, O., Adolfsson, A., Bjärnroos, A., Blennow-Nordström, E., Dragancea, I., Kander, T., Lybeck, A., Mattiasson, G., Persson, O., Rundgren, M., Schrey, S., Annborn, M., Andertun, S., Ebner, F., Gustavsson, N., Hassel, L., Johnsson, J., Nelderup, M., Petersson, H., Petersson, J., Staflidou, F., Undén, J., Antonsson, F., Bergman, G., Gamroth, J., Meirik, M., Rudolfsson, K., Sandberg, H., Thorsson, M., Savolainen, K., Hansbo, M., Helliksson, M., Nödtveidt, B., Sanner, J., Sem, V., Lindquist, C.S., Awad, A., Börjesson, A.S., Hedberg, M., Henning, M., Hollenberg, J., Petersen, P., Dahlberg, E., Forshammar, J., Svensson, V., Wanecek, M., Eskilsson, H., Rodriguez-Santos, D., Appelqvist, Å., Jidbratt, H., Johansson, E., Kiszakiewicz, L., Nilsson, Å., Olsson, S., Paulsson, A., Stempel, U., Thoren, A., Persson, S., Berglund, I., Bergström, E., Törnqvist, C., Östman, I., Rubertsson, S., Larsson, I.M., Söderman, E., Wallin, E., Wessbergh, J., Halliday, T., Engvall, F., Ben-Hamouda, N., Bernini, A., Carron, P.N., Eckert, P., Favre, E., Miroz, J.P., Morelli, P., Muller, O., Novi, J., Rosseti, A., Schnorf, M., Haenggi, M., Levis, A., Nansoz, S., Roth, M., Söll, N., Schrag, C., Alicajic, M., Baier, P., Dütschler, J., Flügel, D., Fässler, E., Gamio-Veis, R., Güpfert, M., Hilpertshauser, Y., Hägele-Link, S., Kleger, G.R., Krähenmann, P., Mair, M.E., Schai, N., Strohmaier, C., Tangl, P., Zieglgänsberger, D., Maggiorini, M., Claus, G., Vogel, G.C., Imbach, L., Kaiser, S., Kleinert, E.M., Garcia, PDW, Cassina, T., Agazzi, P., Capelli, B., Casso, G., Regazzi, M., Schlotterbeck, H., Via, G., Villa, M., Brooks, J., Cocks, E., Cole, J., Curtin, J., Davies, M., Davies, R., Fernandez, S., Highfeld, J., Pennant, L., Rose, S., Thomas, E., Williams, A., McGuigan, P., Hafey, S., O'Neill, A., Ward, K., Thomas, M., Bewley, J., Chillingworth, A., Cloake, J., Cole, L., Galvin, H., Garland, Z., Grimmer, L., Gumbrill, B., Howie, L., Johnson, R., Searles, C., Skorko, A., Sweet, K., Taylor, V., Webster, D., Keeble, T., Adams, G., Aggarwal, R.K., Cartwright, J.A., Church, S., Clesham, G.J., Davies, J.R., Farrell, K., Gamma, R., Harding, J., Jagathesan, R., Kabir, A., Kelly, P.A., Kittridge, L., Maccaroni, M., Maloney, G., Mion, M., Nain, N., Nalgirkar, R., Namjoshi, G., Pepper, S., Redman, E., Robinson, N.M., Sayer, J., Solesbury, A., Tang, K.H., Urovi, S., Waghmare, K., Watson, N., Webber, T., Isherwood, P., Bentley, C., Bergin, C., Carrera, R., Clark, A., Cooper, L., Despy, L., Dooley, N., Ellis, K., Fellows, E., Goundry, S., Harkett, S., McGhee, C., Neal, A., Smith, H., Snelson, C., Spruce, E., Whitehouse, T., Yakoub, K., Walden, A., Bartley, S., Bhuie, P., Frise, M., Jacques, N., Keating, L., Pogson, D., Daly, Z., Bannard-Smith, J., Quayle, R., Chee, N., Barratt, N., Bowman, K., Branney, D., Howe, E., Letts, M., Pitts, S., Vamplew, L., Callaway, C.W., Sprouse, S.D., Doshi, A.A., Fugate, J., Headlee, A.M., Wijdicks, EFM
Zdroj:	Intensive Care Med Intensive care medicine, vol. 50, no. 1, pp. 90-102 Turella, S, Dankiewicz, J, Friberg, H, Jakobsen, J C, Leithner, C, Levin, H, Lilja, G, Moseby-Knappe, M, Nielsen, N, Rossetti, A O, Sandroni, C, Zubler, F, Cronberg, T, Westhall, E, TTM2 Trial Investigators & Lange, T 2024, ' The predictive value of highly malignant EEG patterns after cardiac arrest : evaluation of the ERC-ESICM recommendations ', Intensive Care Medicine, vol. 50, no. 1, pp. 90-102 . https://doi.org/10.1007/s00134-023-07280-9 Turella, Sara; Dankiewicz, Josef; Friberg, Hans; Jakobsen, Janus Christian; Leithner, Christoph; Levin, Helena; Lilja, Gisela; Moseby-Knappe, Marion; Nielsen, Niklas; Rossetti, Andrea O; Sandroni, Claudio; Zubler, Frédéric; Cronberg, Tobias; Westhall, Erik (2024). The predictive value of highly malignant EEG patterns after cardiac arrest: evaluation of the ERC-ESICM recommendations. Intensive care medicine, 50(1), pp. 90-102. Springer 10.1007/s00134-023-07280-9 <http://dx.doi.org/10.1007/s00134-023-07280-9>
Informácie o vydavateľovi:	Springer Science and Business Media LLC, 2024.
Rok vydania:	2024
Predmety:	Heart Arrest/diagnosis, Critical Care, Original, Electroencephalography/methods, 610 Medicine & health, Hypothermia, 12. Responsible consumption, Brain injury, Cardiac arrest, Coma, EEG, Outcome, Prognosis, Hypothermia, Induced, Humans, Multicenter Studies as Topic, Electroencephalography/methods [MeSH], Humans [MeSH], Hypothermia, Induced/methods [MeSH], Multicenter Studies as Topic [MeSH], Critical Care [MeSH], Heart Arrest/diagnosis [MeSH], Clinical Trials as Topic [MeSH], Prognosis [MeSH], Heart Arrest/therapy [MeSH], Cardiopulmonary Resuscitation/methods [MeSH], Eeg, 2. Zero hunger, Clinical Trials as Topic, Electroencephalography, Cardiopulmonary Resuscitation, Heart Arrest, 3. Good health, Induced/methods, Cardiopulmonary Resuscitation/methods
Popis:	The 2021 guidelines endorsed by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) recommend using highly malignant electroencephalogram (EEG) patterns (HMEP; suppression or burst-suppression) at > 24 h after cardiac arrest (CA) in combination with at least one other concordant predictor to prognosticate poor neurological outcome. We evaluated the prognostic accuracy of HMEP in a large multicentre cohort and investigated the added value of absent EEG reactivity.This is a pre-planned prognostic substudy of the Targeted Temperature Management trial 2. The presence of HMEP and background reactivity to external stimuli on EEG recorded > 24 h after CA was prospectively reported. Poor outcome was measured at 6 months and defined as a modified Rankin Scale score of 4-6. Prognostication was multimodal, and withdrawal of life-sustaining therapy (WLST) was not allowed before 96 h after CA.845 patients at 59 sites were included. Of these, 579 (69%) had poor outcome, including 304 (36%) with WLST due to poor neurological prognosis. EEG was recorded at a median of 71 h (interquartile range [IQR] 52-93) after CA. HMEP at > 24 h from CA had 50% [95% confidence interval [CI] 46-54] sensitivity and 93% [90-96] specificity to predict poor outcome. Specificity was similar (93%) in 541 patients without WLST. When HMEP were unreactive, specificity improved to 97% [94-99] (p = 0.008).The specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after CA exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy. Combining HMEP with an unreactive EEG background significantly improved specificity. As in other prognostication studies, a self-fulfilling prophecy bias may have contributed to observed results.
Druh dokumentu:	Article Other literature type
Popis súboru:	application/pdf
Jazyk:	English
ISSN:	1432-1238 0342-4642
DOI:	10.1007/s00134-023-07280-9
DOI:	10.48350/191250
Prístupová URL adresa:	https://pubmed.ncbi.nlm.nih.gov/38172300 https://hdl.handle.net/11368/3073342 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10811097/ https://link.springer.com/article/10.1007/s00134-023-07280-9 https://serval.unil.ch/resource/serval:BIB_B43D2E92358C.P001/REF.pdf https://serval.unil.ch/notice/serval:BIB_B43D2E92358C http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_B43D2E92358C5 https://hdl.handle.net/10807/271267 https://doi.org/10.1007/s00134-023-07280-9 https://curis.ku.dk/ws/files/455554479/s00134-023-07280-9.pdf https://portal.findresearcher.sdu.dk/da/publications/fd91e33c-2ca7-47b0-9fe8-4c96b57b857b https://doi.org/10.1007/s00134-023-07280-9 https://boris.unibe.ch/191250/ https://hdl.handle.net/11368/3073342 https://doi.org/10.1007/s00134-023-07280-9 https://link.springer.com/article/10.1007/s00134-023-07280-9 https://repository.publisso.de/resource/frl:6509798
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Prístupové číslo:	edsair.doi.dedup.....f388b572bed65f3ba5edbcee7e44e616
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Abstrakt:	The 2021 guidelines endorsed by the European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) recommend using highly malignant electroencephalogram (EEG) patterns (HMEP; suppression or burst-suppression) at > 24 h after cardiac arrest (CA) in combination with at least one other concordant predictor to prognosticate poor neurological outcome. We evaluated the prognostic accuracy of HMEP in a large multicentre cohort and investigated the added value of absent EEG reactivity.This is a pre-planned prognostic substudy of the Targeted Temperature Management trial 2. The presence of HMEP and background reactivity to external stimuli on EEG recorded > 24 h after CA was prospectively reported. Poor outcome was measured at 6 months and defined as a modified Rankin Scale score of 4-6. Prognostication was multimodal, and withdrawal of life-sustaining therapy (WLST) was not allowed before 96 h after CA.845 patients at 59 sites were included. Of these, 579 (69%) had poor outcome, including 304 (36%) with WLST due to poor neurological prognosis. EEG was recorded at a median of 71 h (interquartile range [IQR] 52-93) after CA. HMEP at > 24 h from CA had 50% [95% confidence interval [CI] 46-54] sensitivity and 93% [90-96] specificity to predict poor outcome. Specificity was similar (93%) in 541 patients without WLST. When HMEP were unreactive, specificity improved to 97% [94-99] (p = 0.008).The specificity of the ERC-ESICM-recommended EEG patterns for predicting poor outcome after CA exceeds 90% but is lower than in previous studies, suggesting that large-scale implementation may reduce their accuracy. Combining HMEP with an unreactive EEG background significantly improved specificity. As in other prognostication studies, a self-fulfilling prophecy bias may have contributed to observed results.
ISSN:	14321238 03424642
DOI:	10.1007/s00134-023-07280-9