Adverse Outcome of a Solitary Fibrous Tumor Originating in the Bladder
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| Title: | Adverse Outcome of a Solitary Fibrous Tumor Originating in the Bladder |
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| Authors: | Takato Nishino, Masaki Shimbo, Eri Fukagawa, Kazutaka Narimoto, Jun Hashimoto, Shin Ogita, Naoki Kanomata, Kazunori Hattori, Fumiyasu Endo |
| Source: | IJU Case Rep IJU Case Reports, Vol 8, Iss 3, Pp 231-235 (2025) |
| Publisher Information: | Wiley, 2025. |
| Publication Year: | 2025 |
| Subject Terms: | robot‐assisted surgery, solitary fibrous tumor, Case Report, RC870-923, poor prognosis, metastases, urinary bladder, Diseases of the genitourinary system. Urology |
| Description: | IntroductionSolitary fibrous tumors originating in the bladder are extremely rare. While generally associated with favorable outcomes, some show invasive behavior. We report a case of a solitary fibrous tumor originating in the bladder that was treated with multimodal therapy.Case PresentationA 68‐year‐old male presented with urinary retention. Imaging revealed a well‐defined 6.0 cm mass compressing the prostate. A biopsy suggested stromal sarcoma. Robot‐assisted cystoprostatectomy was performed. Pathological examination revealed a solitary fibrous tumor originating from the bladder invading the prostate. Despite negative margins, lung nodules and a pelvic mass appeared 43 months postoperatively. Initially, these were treated with pazopanib, followed by doxorubicin and eribulin due to disease progression. The patient eventually transitioned to palliative care and passed away 69 months after diagnosis.ConclusionThere are no effective systemic treatments for solitary fibrous tumors, which can lead to poor outcomes. Individualized treatment approaches are necessary. |
| Document Type: | Article Other literature type |
| Language: | English |
| ISSN: | 2577-171X |
| DOI: | 10.1002/iju5.70013 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/40336741 https://doaj.org/article/8c0243576fcd4c5297c332ee317f3308 |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....f1ebc3d6dceba87d84ec7062325e8c04 |
| Database: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | IntroductionSolitary fibrous tumors originating in the bladder are extremely rare. While generally associated with favorable outcomes, some show invasive behavior. We report a case of a solitary fibrous tumor originating in the bladder that was treated with multimodal therapy.Case PresentationA 68‐year‐old male presented with urinary retention. Imaging revealed a well‐defined 6.0 cm mass compressing the prostate. A biopsy suggested stromal sarcoma. Robot‐assisted cystoprostatectomy was performed. Pathological examination revealed a solitary fibrous tumor originating from the bladder invading the prostate. Despite negative margins, lung nodules and a pelvic mass appeared 43 months postoperatively. Initially, these were treated with pazopanib, followed by doxorubicin and eribulin due to disease progression. The patient eventually transitioned to palliative care and passed away 69 months after diagnosis.ConclusionThere are no effective systemic treatments for solitary fibrous tumors, which can lead to poor outcomes. Individualized treatment approaches are necessary. |
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| ISSN: | 2577171X |
| DOI: | 10.1002/iju5.70013 |